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From the first issue of 2016, Chromatography has changed its name to Separations.

Open AccessReview
Chromatography 2014, 1(1), 24-53; doi:10.3390/chromatography1010024

Post-Polymerization Modifications of Polymeric Monolithic Columns: A Review

Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, Pardubice 532 10, Czech Republic
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Received: 18 December 2013 / Revised: 16 January 2014 / Accepted: 17 January 2014 / Published: 10 February 2014
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Abstract

The vast cache of methods used in polymeric monolithic column modification is presented herein, with specific attention to post-polymerization modification reactions. The modification of polymeric monolithic columns is defined and can include the modification of pre-existing surface groups, the addition of polymeric chains or indeed the addition of structures such as nano-particles and nano-structures. The use of these modifications can result in the specific patterning of monoliths, useful in microfluidic device design or in the investigation of modification optimization.
Keywords: polymer monoliths; modifications; HPLC; CEC; grafting; click chemistry; hypercross-linking; nano-particles polymer monoliths; modifications; HPLC; CEC; grafting; click chemistry; hypercross-linking; nano-particles
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Currivan, S.; Jandera, P. Post-Polymerization Modifications of Polymeric Monolithic Columns: A Review. Chromatography 2014, 1, 24-53.

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