Target,Common name,Uniprot ID,ChEMBL ID,Target Class,Probability*,Known actives (3D/2D),,
NADPH oxidase 4,NOX4,Q9NPH5,CHEMBL1250375,Enzyme,1,6 /  8     ,,Apigenin
Aldose reductase   (by homology),AKR1B1,P15121,CHEMBL1900,Enzyme,1,17 /  70     ,,Apigenin
Cyclin-dependent kinase 5/CDK5 activator 1,CDK5R1 CDK5,Q15078 Q00535,CHEMBL1907600,Kinase,1,6 /  18     ,,Apigenin
Xanthine dehydrogenase,XDH,P47989,CHEMBL1929,Oxidoreductase,1,12 /  20     ,,Apigenin
Monoamine oxidase A,MAOA,P21397,CHEMBL1951,Oxidoreductase,1,6 /  26     ,,Apigenin
Tyrosine-protein kinase receptor FLT3,FLT3,P36888,CHEMBL1974,Kinase,1,6 /  7     ,,Apigenin
Cytochrome P450 19A1,CYP19A1,P11511,CHEMBL1978,Cytochrome P450,1,6 /  19     ,,Apigenin
Estrogen receptor alpha,ESR1,P03372,CHEMBL206,Nuclear receptor,1,76 /  49     ,,Apigenin
Cyclin-dependent kinase 1/cyclin B,CCNB3 CDK1 CCNB1 CCNB2,Q8WWL7 P06493 P14635 O95067,CHEMBL2094127,Other cytosolic protein,1,4 /  12     ,,Apigenin
Acetylcholinesterase,ACHE,P22303,CHEMBL220,Hydrolase,1,4 /  26     ,,Apigenin
Adenosine A1 receptor   (by homology),ADORA1,P30542,CHEMBL226,Family A G protein-coupled receptor,1,6 /  23     ,,Apigenin
Cyclooxygenase-2,PTGS2,P35354,CHEMBL230,Oxidoreductase,1,2 /  11     ,,Apigenin
Estrogen receptor beta,ESR2,Q92731,CHEMBL242,Nuclear receptor,1,96 /  52     ,,Apigenin
Cyclin-dependent kinase 6,CDK6,Q00534,CHEMBL2508,Kinase,1,3 /  4     ,,Apigenin
Adenosine A2a receptor   (by homology),ADORA2A,P29274,CHEMBL251,Family A G protein-coupled receptor,1,5 /  11     ,,Apigenin
Tyrosine-protein kinase SYK,SYK,P43405,CHEMBL2599,Kinase,1,3 /  3     ,,Apigenin
Glycogen synthase kinase-3 beta,GSK3B,P49841,CHEMBL262,Kinase,1,3 /  7     ,,Apigenin
Multidrug resistance-associated protein 1,ABCC1,P33527,CHEMBL3004,Primary active transporter,1,7 /  11     ,,Apigenin
Estradiol 17-beta-dehydrogenase 1,HSD17B1,P14061,CHEMBL3181,Enzyme,1,9 /  4     ,,Apigenin
Transthyretin,TTR,P02766,CHEMBL3194,Secreted protein,1,2 /  2     ,,Apigenin
Casein kinase II alpha,CSNK2A1,P68400,CHEMBL3629,Kinase,1,4 /  2     ,,Apigenin
Cystic fibrosis transmembrane conductance regulator,CFTR,P13569,CHEMBL4051,Other ion channel,1,1 /  1     ,,Apigenin
Cytochrome P450 1B1,CYP1B1,Q16678,CHEMBL4878,Cytochrome P450,1,12 /  47     ,,Apigenin
ATP-binding cassette sub-family G member 2,ABCG2,Q9UNQ0,CHEMBL5393,Primary active transporter,1,6 /  47     ,,Apigenin
Aldo-keto reductase family 1 member B10,AKR1B10,O60218,CHEMBL5983,Enzyme,1,2 /  3     ,,Apigenin
Tankyrase-2,TNKS2,Q9H2K2,CHEMBL6154,Enzyme,1,4 /  12     ,,Apigenin
Tankyrase-1,TNKS,O95271,CHEMBL6164,Enzyme,1,4 /  28     ,,Apigenin
Arachidonate 5-lipoxygenase,ALOX5,P09917,CHEMBL215,Oxidoreductase,0.608509241,5 /  46     ,,Apigenin
Poly [ADP-ribose] polymerase-1,PARP1,P09874,CHEMBL3105,Enzyme,0.608509241,3 /  9     ,,Apigenin
Carbonic anhydrase II,CA2,P00918,CHEMBL205,Lyase,0.542899854,8 /  15     ,,Apigenin
Carbonic anhydrase VII,CA7,P43166,CHEMBL2326,Lyase,0.542899854,8 /  11     ,,Apigenin
Carbonic anhydrase XII,CA12,O43570,CHEMBL3242,Lyase,0.542899854,10 /  16     ,,Apigenin
P-glycoprotein 1,ABCB1,P08183,CHEMBL4302,Primary active transporter,0.542899854,12 /  47     ,,Apigenin
Arachidonate 12-lipoxygenase,ALOX12,P18054,CHEMBL3687,Enzyme,0.493789288,9 /  11     ,,Apigenin
Carbonic anhydrase IV,CA4,P22748,CHEMBL3729,Lyase,0.485540261,7 /  11     ,,Apigenin
Receptor-type tyrosine-protein phosphatase S,PTPRS,Q13332,CHEMBL2396508,Phosphatase,0.411906406,7 /  8     ,,Apigenin
Glyoxalase I,GLO1,Q04760,CHEMBL2424,Enzyme,0.370888463,3 /  4     ,,Apigenin
Beta amyloid A4 protein,APP,P05067,CHEMBL2487,Membrane receptor,0.370888463,2 /  13     ,,Apigenin
Matrix metalloproteinase 9,MMP9,P14780,CHEMBL321,Protease,0.370888463,2 /  2     ,,Apigenin
Matrix metalloproteinase 2,MMP2,P08253,CHEMBL333,Protease,0.370888463,2 /  2     ,,Apigenin
Matrix metalloproteinase 12,MMP12,P39900,CHEMBL4393,Protease,0.370888463,1 /  1     ,,Apigenin
Lymphocyte differentiation antigen CD38,CD38,P28907,CHEMBL4660,Enzyme,0.370888463,2 /  2     ,,Apigenin
DNA topoisomerase I   (by homology),TOP1,P11387,CHEMBL1781,Isomerase,0.370888463,1 /  1     ,,Apigenin
Arginase-1   (by homology),ARG1,P05089,CHEMBL1075097,Enzyme,0.370888463,2 /  2     ,,Apigenin
Estrogen-related receptor alpha,ESRRA,P11474,CHEMBL3429,Nuclear receptor,0.362674719,2 /  2     ,,Apigenin
"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3",PFKFB3,Q16875,CHEMBL2331053,Enzyme,0.33811031,2 /  2     ,,Apigenin
AMY1C,AMY1A,P04745,CHEMBL2478,Enzyme,0.33811031,1 /  1     ,,Apigenin
G protein-coupled receptor kinase 6,GRK6,P43250,CHEMBL6144,Kinase,0.33811031,2 /  4     ,,Apigenin
Arachidonate 15-lipoxygenase,ALOX15,P16050,CHEMBL2903,Enzyme,0.329868485,6 /  8     ,,Apigenin
Tyrosinase,TYR,P14679,CHEMBL1973,Oxidoreductase,0.264392858,2 /  3     ,,Apigenin
Estradiol 17-beta-dehydrogenase 2,HSD17B2,P37059,CHEMBL2789,Enzyme,0.264392858,9 /  3     ,,Apigenin
Aryl hydrocarbon receptor,AHR,P35869,CHEMBL3201,Transcription factor,0.264392858,1 /  1     ,,Apigenin
Carbonic anhydrase I,CA1,P00915,CHEMBL261,Lyase,0.25622784,4 /  7     ,,Apigenin
Carbonic anhydrase IX,CA9,Q16790,CHEMBL3594,Lyase,0.25622784,3 /  7     ,,Apigenin
Carbonyl reductase [NADPH] 1,CBR1,P16152,CHEMBL5586,Enzyme,0.247942823,3 /  2     ,,Apigenin
Androgen Receptor,AR,P10275,CHEMBL1871,Nuclear receptor,0.247942823,0 /  16     ,,Apigenin
Telomerase reverse transcriptase,TERT,O14746,CHEMBL2916,Enzyme,0.239574696,9 /  21     ,,Apigenin
Serine/threonine-protein kinase PIM1,PIM1,P11309,CHEMBL2147,Kinase,0.239574696,8 /  7     ,,Apigenin
Epidermal growth factor receptor erbB1,EGFR,P00533,CHEMBL203,Kinase,0.207053974,9 /  30     ,,Apigenin
Cyclin-dependent kinase 1,CDK1,P06493,CHEMBL308,Kinase,0.190656977,3 /  10     ,,Apigenin
Lysine-specific demethylase 4D-like,KDM4E,B2RXH2,CHEMBL1293226,Eraser,0.166097445,2 /  2     ,,Apigenin
Tyrosine-protein kinase LCK,LCK,P06239,CHEMBL258,Kinase,0.149732594,5 /  3     ,,Apigenin
Serine/threonine-protein kinase Aurora-B,AURKB,Q96GD4,CHEMBL2185,Kinase,0.149732594,3 /  4     ,,Apigenin
Thromboxane-A synthase,TBXAS1,P24557,CHEMBL1835,Cytochrome P450,0.141522086,1 /  2     ,,Apigenin
NEDD8-activating enzyme E1 regulatory subunit,NAE1,Q13564,CHEMBL2016431,Unclassified protein,0.141522086,0 /  1     ,,Apigenin
Insulin-like growth factor I receptor,IGF1R,P08069,CHEMBL1957,Kinase,0.133337961,3 /  3     ,,Apigenin
Vascular endothelial growth factor receptor 2,KDR,P35968,CHEMBL279,Kinase,0.125142649,2 /  3     ,,Apigenin
Serine/threonine-protein kinase PLK1,PLK1,P53350,CHEMBL3024,Kinase,0.125142649,2 /  3     ,,Apigenin
Hepatocyte growth factor receptor,MET,P08581,CHEMBL3717,Kinase,0.125142649,4 /  4     ,,Apigenin
ALK tyrosine kinase receptor,ALK,Q9UM73,CHEMBL4247,Kinase,0.125142649,2 /  4     ,,Apigenin
Tyrosine-protein kinase receptor UFO,AXL,P30530,CHEMBL4895,Kinase,0.125142649,2 /  4     ,,Apigenin
Butyrylcholinesterase,BCHE,P06276,CHEMBL1914,Hydrolase,0.125142649,1 /  7     ,,Apigenin
Adenosine A3 receptor,ADORA3,P0DMS8,CHEMBL256,Family A G protein-coupled receptor,0.125142649,1 /  21     ,,Apigenin
Cyclin-dependent kinase 2,CDK2,P24941,CHEMBL301,Kinase,0.125142649,1 /  12     ,,Apigenin
Serotonin 2c (5-HT2c) receptor,HTR2C,P28335,CHEMBL225,Family A G protein-coupled receptor,0.125142649,1 /  2     ,,Apigenin
G-protein coupled receptor 35,GPR35,Q9HC97,CHEMBL1293267,Family A G protein-coupled receptor,0.116965063,2 /  4     ,,Apigenin
Death-associated protein kinase 1,DAPK1,P53355,CHEMBL2558,Kinase,0.116965063,2 /  2     ,,Apigenin
DNA-3-methyladenine glycosylase,MPG,P29372,CHEMBL3396943,Enzyme,0.116965063,1 /  1     ,,Apigenin
Solute carrier family 22 member 12,SLC22A12,Q96S37,CHEMBL6120,Electrochemical transporter,0.116965063,6 /  1     ,,Apigenin
Thrombin,F2,P00734,CHEMBL204,Protease,0.108770969,11 /  3     ,,Apigenin
"Beta-galactoside alpha-2,6-sialyltransferase 1",ST6GAL1,P15907,CHEMBL3596075,Transferase,0.108770969,0 /  2     ,,Apigenin
Plasminogen,PLG,P00747,CHEMBL1801,Protease,0.108770969,6 /  3     ,,Apigenin
Vasopressin V2 receptor,AVPR2,P30518,CHEMBL1790,Family A G protein-coupled receptor,0.108770969,1 /  1     ,,Apigenin
Dopamine D4 receptor,DRD4,P21917,CHEMBL219,Family A G protein-coupled receptor,0.108770969,1 /  1     ,,Apigenin
Myeloperoxidase,MPO,P05164,CHEMBL2439,Enzyme,0.108770969,1 /  1     ,,Apigenin
PI3-kinase p85-alpha subunit,PIK3R1,P27986,CHEMBL2506,Enzyme,0.108770969,1 /  1     ,,Apigenin
Liver glycogen phosphorylase,PYGL,P06737,CHEMBL2568,Enzyme,0.108770969,1 /  1     ,,Apigenin
Tyrosine-protein kinase SRC,SRC,P12931,CHEMBL267,Kinase,0.108770969,5 /  8     ,,Apigenin
Focal adhesion kinase 1,PTK2,Q05397,CHEMBL2695,Kinase,0.108770969,1 /  2     ,,Apigenin
Matrix metalloproteinase 13,MMP13,P45452,CHEMBL280,Protease,0.108770969,1 /  1     ,,Apigenin
Matrix metalloproteinase 3,MMP3,P08254,CHEMBL283,Protease,0.108770969,1 /  1     ,,Apigenin
Carbonic anhydrase III,CA3,P07451,CHEMBL2885,Lyase,0.108770969,1 /  2     ,,Apigenin
Carbonic anhydrase VI,CA6,P23280,CHEMBL3025,Lyase,0.108770969,1 /  1     ,,Apigenin
Protein kinase N1,PKN1,Q16512,CHEMBL3384,Kinase,0.108770969,1 /  3     ,,Apigenin
Carbonic anhydrase XIV,CA14,Q9ULX7,CHEMBL3510,Lyase,0.108770969,1 /  2     ,,Apigenin
Serine/threonine-protein kinase NEK2,NEK2,P51955,CHEMBL3835,Kinase,0.108770969,1 /  2     ,,Apigenin
Interleukin-8 receptor A,CXCR1,P25024,CHEMBL4029,Family A G protein-coupled receptor,0.108770969,1 /  1     ,,Apigenin
CaM kinase II beta,CAMK2B,Q13554,CHEMBL4121,Kinase,0.108770969,1 /  2     ,,Apigenin
Serine/threonine-protein kinase AKT,AKT1,P31749,CHEMBL4282,Kinase,0.108770969,1 /  4     ,,Apigenin
Serine/threonine-protein kinase NEK6,NEK6,Q9HC98,CHEMBL4309,Kinase,0.108770969,1 /  2     ,,Apigenin
