### Model # 430

Prediction statistics
Endpoint | Concordance | Sensitivity | Specificity | #chemicals
--- | --- | --- | --- | ---
Developmental Toxicity | 0,977 (43 out of 44) | 1,000 (37 out of 37) | 0,857 (6 out of 7) | 44

Model coefficients
Coefficient | Definition | Value | Uncertainty*
--- | --- | --- | ---
Intercept | Model intercept | 3,3764 | 1,1295
SsssN_acnt | Count of ( > N – ) (SsssN_acnt) | 0,1013 | 0,0866
BELe8 | Lowest eigenvalue n. 8 of Burden matrix / weighted by atomic Sanderson electronegativities | -1,3387 | 0,6786
ATS8m | Broto-Moreau autocorrelation of a topological structure - lag 8 / weighted by atomic masses | 0,4048 | 0,1350
ATS5v | Broto-Moreau autocorrelation of a topological structure - lag 5 / weighted by atomic van der Waals volumes | -0,6556 | 0,3090
MATS6m | Moran autocorrelation - lag 6 / weighted by atomic masses | -0,4445 | 0,3953
GATS3m | Geary autocorrelation - lag 3 / weighted by atomic masses | 0,2459 | 0,2354
piID | Conventional bond order id number | -0,0053 | 0,0038
-C(=O)- [2 aromatic attach] | -C(=O)- [2 aromatic attach] fragment count | -0,7104 | 0,3224

* value for 90% confidence interval

Model equation:
Developmental Toxicity = 0,1013×(SsssN_acnt) - 1,3387×(BELe8) + 0,4048×(ATS8m) - 0,6556×(ATS5v) - 0,4445×(MATS6m) + 0,2459×(GATS3m) - 0,0053×(piID) - 0,7104×(-C(=O)- [2 aromatic attach]) + 3,3764

Model 430 fit results by chemical Model 430 training set descriptors