### Neurotoxicity Model

Parameter | Value
--- | ---
Endpoint | Fathead minnow LC50 (96 hr)
r2 | 0,902
q2 | 0,829
#chemicals | 22
Model | Neurotoxicity Model

Model coefficients
Coefficient | Definition | Value | Uncertainty*
--- | --- | --- | ---
Intercept | Model intercept | 5,6249 | 0,6991
BELe4 | Lowest eigenvalue n. 4 of Burden matrix / weighted by atomic Sanderson electronegativities | 1,9800 | 0,5518
MATS4m | Moran autocorrelation - lag 4 / weighted by atomic masses | -4,1108 | 1,1935
MATS3p | Moran autocorrelation - lag 3 / weighted by atomic polarizabilities | 5,1188 | 1,7596
GATS8e | Geary autocorrelation - lag 8 / weighted by atomic Sanderson electronegativities | -0,6009 | 0,2523

* value for 90% confidence interval

Model equation:
Fathead minnow LC50 (96 hr) = 1,9800×(BELe4) - 4,1108×(MATS4m) + 5,1188×(MATS3p) - 0,6009×(GATS8e) + 5,6249

Neurotoxicity LC50 fit results by chemical Neurotoxicity LC50 training set descriptors