Microparticle Inertial Focusing in an Asymmetric Curved Microchannel
Abstract
:1. Introduction
2. Theoretical Background
3. Materials and Methods
3.1. Microchannel Fabrication
3.2. Particle Suspensions
3.3. Experimentation
3.4. Fluorescent Imaging and Data Analysis
4. Results and Discussion
4.1. Large Particles
4.2. Medium Particles
4.3. Small Particles
4.4. Discussion
5. Conclusions
- The focusing of large particles occurred in the transition region over a band having a width of approximately 1.5 times the diameter of a single particle for the Reynolds numbers between 106 and 205, while the focusing width was at least six times that value in the outlet region over the same range.
- Medium particles covered a band having a width of 1.5 times the diameter of a single particle in the transition region for Re range of 61–136. They focused in a line as wide as the diameter of a single particle for values between 76 and 167 in the outlet region.
- The minimum width of the focusing band of the small particles in the transition region was 3.6 times the diameter of a single particle at of 98. This value for the outlet region was at least ten times the diameter of a single particle.
- The focusing behavior of the small particles in the proposed asymmetric microchannel significantly differs from that in the symmetric channel. The dissimilarities include narrower focusing band and noticeable distance from the wall W2 in the asymmetric microchannel.
- Placing the outlets at the transition region implies the potential use of the proposed geometry in particle or cell separation applications. At of 121, the streams of the large and small particles were separated by the largest distance, similar to the medium and small particles. The separation of the large and medium particles was obtained at of 144, with a distance of around two times the diameter of large particles.
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Özbey, A.; Karimzadehkhouei, M.; Alijani, H.; Koşar, A. Microparticle Inertial Focusing in an Asymmetric Curved Microchannel. Fluids 2018, 3, 57. https://doi.org/10.3390/fluids3030057
Özbey A, Karimzadehkhouei M, Alijani H, Koşar A. Microparticle Inertial Focusing in an Asymmetric Curved Microchannel. Fluids. 2018; 3(3):57. https://doi.org/10.3390/fluids3030057
Chicago/Turabian StyleÖzbey, Arzu, Mehrdad Karimzadehkhouei, Hossein Alijani, and Ali Koşar. 2018. "Microparticle Inertial Focusing in an Asymmetric Curved Microchannel" Fluids 3, no. 3: 57. https://doi.org/10.3390/fluids3030057