Antibiotics in Animal Health

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: closed (28 February 2017) | Viewed by 31438

Special Issue Editor


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Guest Editor
School of Pharmacy and Medical Sciences, University of South Australia, City East Campus, Playford Building, P4-38, Frome Road, Adelaide, SA 5000, Australia
Interests: antibiotic resistance; alternatives to antibiotics; role of animals in epidemiology of antibiotic resistance in humans and vice versa
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antibiotic resistance is a global challenge in human and veterinary medicine. Continued access to antibiotics is critical to livestock and aquaculture production and for the health and welfare of companion animals. However, use of antibiotics in animals must be managed well.

Issues that need to be considered include:

  • How antibiotics are used in animals and the quantities that are used
  • Use of antibiotics of critical importance in human medicine in animals
  • Epidemiology and surveillance of antibiotic resistance in commensal and pathogenic bacteria isolated from animals
  • Role of animals in the transfer of antibiotic resistant organisms and genes to humans and vice versa
  • Environmental contamination associated with the use of antibiotics in animals (including aquaculture)
  • Alternatives to antibiotics

Prof. Dr. Mary Barton
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Antibiotic
  • antibiotic resistance
  • monitoring and surveillance
  • epidemiology of antibiotic resistance
  • alternatives to antibiotics
  • antimicrobial stewardship

Published Papers (2 papers)

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Review

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Review
Bacteria from Animals as a Pool of Antimicrobial Resistance Genes
by Maria Angeles Argudín, Ariane Deplano, Alaeddine Meghraoui, Magali Dodémont, Amelie Heinrichs, Olivier Denis, Claire Nonhoff and Sandrine Roisin
Antibiotics 2017, 6(2), 12; https://doi.org/10.3390/antibiotics6020012 - 06 Jun 2017
Cited by 175 | Viewed by 11898
Abstract
Antimicrobial agents are used in both veterinary and human medicine. The intensive use of antimicrobials in animals may promote the fixation of antimicrobial resistance genes in bacteria, which may be zoonotic or capable to transfer these genes to human-adapted pathogens or to human [...] Read more.
Antimicrobial agents are used in both veterinary and human medicine. The intensive use of antimicrobials in animals may promote the fixation of antimicrobial resistance genes in bacteria, which may be zoonotic or capable to transfer these genes to human-adapted pathogens or to human gut microbiota via direct contact, food or the environment. This review summarizes the current knowledge of the use of antimicrobial agents in animal health and explores the role of bacteria from animals as a pool of antimicrobial resistance genes for human bacteria. This review focused in relevant examples within the ESC(K)APE (Enterococcus faecium, Staphylococcus aureus, Clostridium difficile (Klebsiella pneumoniae), Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae) group of bacterial pathogens that are the leading cause of nosocomial infections throughout the world. Full article
(This article belongs to the Special Issue Antibiotics in Animal Health)
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1206 KiB  
Review
Antimicrobial Usage and Antimicrobial Resistance in Animal Production in Southeast Asia: A Review
by Nguyen T. Nhung, Nguyen V. Cuong, Guy Thwaites and Juan Carrique-Mas
Antibiotics 2016, 5(4), 37; https://doi.org/10.3390/antibiotics5040037 - 02 Nov 2016
Cited by 137 | Viewed by 18881
Abstract
Southeast Asia is an area of great economic dynamism. In recent years, it has experienced a rapid rise in the levels of animal product production and consumption. The region is considered to be a hotspot for infectious diseases and antimicrobial resistance (AMR). We [...] Read more.
Southeast Asia is an area of great economic dynamism. In recent years, it has experienced a rapid rise in the levels of animal product production and consumption. The region is considered to be a hotspot for infectious diseases and antimicrobial resistance (AMR). We reviewed English-language peer-reviewed publications related to antimicrobial usage (AMU) and AMR in animal production, as well as antimicrobial residues in meat and fish from 2000 to 2016, in the region. There is a paucity of data from most countries and for most bacterial pathogens. Most of the published work relates to non-typhoidal Salmonella (NTS), Escherichia coli (E. coli), and Campylobacter spp. (mainly from Vietnam and Thailand), Enterococcus spp. (Malaysia), and methicillin-resistant Staphylococcus aureus (MRSA) (Thailand). However, most studies used the disk diffusion method for antimicrobial susceptibility testing; breakpoints were interpreted using Clinical Standard Laboratory Institute (CSLI) guidelines. Statistical models integrating data from publications on AMR in NTS and E. coli studies show a higher overall prevalence of AMR in pig isolates, and an increase in levels of AMR over the years. AMU studies (mostly from Vietnam) indicate very high usage levels of most types of antimicrobials, including beta-lactams, aminoglycosides, macrolides, and quinolones. This review summarizes information about genetic determinants of resistance, most of which are transferrable (mostly plasmids and integrons). The data in this review provide a benchmark to help focus research and policies on AMU and AMR in the region. Full article
(This article belongs to the Special Issue Antibiotics in Animal Health)
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