Nanoparticles for Delivery of Immunotherapy

Dear Colleagues,

This Special Issue, “Nanoparticles for Delivery of Immunotherapy”, will focus on the fabrication and biological testing of nanoplatforms for vaccine development and immune modulation.

Recent advances in nanomedicine for cancer applications have provided diverse groups of synthetic particles with defined cellular and biological functions. Lipid, silicon, gold, iron oxide, and polymeric particles, as well as virus and virus-like particles, have been used to facilitate antigen delivery, with concurrent delivery of antigens and adjuvant serving to enhance adaptive immunity. Alternatively, delivery of nano immune modulators with cytotoxic agents, such as chemotherapeutics, enhances weak cancer specific immune responses. Benefits of particle-based carriers include long-term release of antigens or immune modulators, oriented antigen and/or adjuvant presentation, multivalent presentation, and targeting.

We invite authors to submit original research and review articles that focus on novel immunomodulatory nanoparticles. Potential topics include, but are not limited to:

• Fabrication of novel immunomodulatory nanoparticles
• Nanoparticles for activation of antigen presenting cells
• Nanoparticles for targeting T cells and/or checkpoint regulators
• Nanoparticles as pathogen mimetics
• Scaffolds containing nanoimmunomodulators for sustained activation of immune cells or as platforms to attract immune cells
• Nanoparticle-based vaccines
• Bi-functional nanoparticles for dual targeting

Dr. Rita Elena Serda
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• nanoparticle
• antigen
• presenting cell
• T cell
• lymph node
• cancer adjuvant
• cytokine
• dendritic cell