Dear Colleagues,

Borderline Personality Disorder (BPD) is a severe mental disorder, characterized by pronounced disturbances in emotion processing and regulation, identity alterations, dissociation, impulsivity, and interpersonal problems. BPD affects about 1.3% of the general population, with a lifetime prevalence of approximately 3–5.9%. Current conceptualizations suggest that a complex interplay of genetic, neurobiological predispositions, adverse life events (e.g., interpersonal trauma), maladaptive cognitive schemata (negative beliefs about the self and others), and dysfunctional stress coping contributes to the development and maintenance of the disorder. With respect to the neurobiology, a growing number of neuroimaging studies observed structural and functional abnormalities in a fronto-limbic brain regions (including amygdala, insula, anterior cingulate cortex, medial frontal cortex, orbitofrontal cortex, and dorsolateral prefrontal cortex) and in regions of the default-mode network, which may underlie disturbed emotion processing in BPD. More and more studies have also provided evidence for altered functional connectivity in large-scale brain networks during rest and during emotion processing in BPD. This Special Issue encourages submissions, which provide further insight into the psychopathology, diagnosis, and treatment of BPD. This includes original articles based on experimental research and neuroimaging studies applying novel techniques, as well as review articles and meta-analyses, which may enhance the understanding of processes and mechanisms underlying and maintaining BPD.

Dr. Robert Dudas
Guest Editor

Manuscript Submission Information

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• Borderline Personality Disorder
• Emotion Dysregulation
• Dissociation
• Self-harming
• Functional Magnetic Resonance Imaging
• Neuroimaging
• Brain function
• Diagnosis
• Treatment