Epidermal Barrier Structure and Function
A special issue of Cosmetics (ISSN 2079-9284).
Deadline for manuscript submissions: closed (31 January 2017)
Special Issue Editor
Interests: skin physiology; irritant contact dermatitis; in vivo Raman spectroscopy; optical coherence tomography; anti-oxidant network of the epidermis; acne vulgaris; itch; urticaria
Special Issue Information
Dear Colleagues,
The understanding of skin barrier has improved considerably over the last few years. In the 1980s, the brick and mortar model was introduced. The epidermal barrier is the main component of the protective barrier separating the inner milieu of the human body from the sometimes harsh environment. During post-natal development, the morphological and functional maturation process leads to a fully competent barrier. The understanding of protective functions, as well as the penetration barrier to externally applied substances, have been studied extensively. The discovery of mutations related to the barrier function has led to a better understanding of the interaction of structural and functional alterations in some dermatosis, e.g., atopic dermatitis. Furthermore, the interaction of barrier alterations and the immune response are the focus of recent research. The present Special Issue on “Epidermal Barrier Structure and Function” will be composed of original papers, reviews and short communications, and should give an overview of the current knowledge in this field.
Prof. Dr. Joachim W. Fluhr
Guest Editor
Keywords
- Epidermis
- Stratum corneum
- Barrier function
- Hydration
- Irritation
- Cosmetic
- Morphology
- Measurements
- In vitro models
- Children skin
- Immune system
- Penetration
