Special Issue "Exploring the Genotype–Phenotype Map to Explain Complex Traits"
Deadline for manuscript submissions: closed (30 June 2017)
Prof. Klaus Wimmers
Leibniz Institute for Farm Animal Biology (FBN), Institute of Genome, Biology, Genomics Unit, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany
Interests: animal genomics; transcriptome; epigenome; animal health; animal welfare
This Special Issue addresses studies along the genotype–phenotype map, aiming at unraveling the genetic foundation of complex quantitative traits.
The appearance of higher organisms is the result of the interaction of environmental factors and many genes. In fact, most properties of plants, animals, and humans depend on the activity of many genes and different modes of interaction along the genotype–phenotype map. The emergence of holistic approaches to analyze the genome, epigenome, transcriptome, proteome, and metabolome provide new opportunities to follow the transition of the genetic potential, which is detailed in the genome, into the final organismal phenotype. The integration of ‘omics’ data and systems biological approaches enable the detection of molecular pathways that are responsible for complex traits and that mediate the interaction of the genotype and the environment. The Special Issue, “Exploring the Genotype–Phenotype Map to Explain Complex Traits”, covers research papers and reviews of studies in man, model organisms, plants, and animals, which are driven by the goal of explaining the determination of a trait based on ‘omics’ data and complementary bioinformatics and systems biology strategies.
Prof. Klaus Wimmers
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- functional networks
- pathway analysis
- quantitative trait
- next generation (exome) sequencing
- gene polymorphisms
- genetic causation
- gene expression
- non-coding RNAs