microRNAs in Cardiovascular Diseases

Dear Colleagues,

microRNAs are short non-coding RNAs that control gene expression at the posttranscrptional level. Each miRNA can potentially target hundreds of genes, causing their down-modulation through translational repression and/or mRNA destabilization. Due to the central role of miRNAs in the control of gene expression, their levels must be tightly controlled. As such, dysregulation of miRNAs expression can result in an excessive or defective miRNAs levels and leads to pathological consequences. miRNAs play a key role in regulating cellular and molecular mechanisms in the cardiovascular system and are involved in cardiovascular disease pathogenesis such as hypertension, atherosclerosis, coronary artery disease, myocardial infarction and heart failure. Furthermore, miRNAs exist in circulating blood and are relatively stable, thus, they could be proved useful as biomarkers in the cardiovascular disease. Therefore, this Special Issue will cover the state-of-the-art on the role of microRNA as biomarkers for diagnosis and for potential therapeutic tools in cardiovascular disease.

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• microRNAs
• circulating microRNA
• cardiovascular disease
• oxidative stress
• hypertension