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Special Issue Editor

Special Issue Information

Dear Colleagues,

Image-guided medicine is rapidly growing to improve treatment regimens as advancing medical imaging, including magnetic resonance imaging (MRI), computed tomography (CT), radiography, ultrasound, positron emission tomography (PET), and single photon emission computed tomography (SPECT). A combination of modern nanoplatforms with high performance in imaging and therapeutics may be critical to improve medical outcomes. One of emerging fields is the image guided therapy using various nanoparticles. Those are including basic bench, preclinical in vitro/in vivo and clinical researches combining synthesis of multimodal nanoparticle and tracking/navigation tools to improve accuracy and outcomes of the therapeutics. Most of the emerging interventional technique such as heat activated targeted drug delivery, image guided ablation (microwave or HIFU), percutaneous injection gene/bacteria therapy, transcatheter treatments for tumor specific local therapy, serial biopsy, thrombolytic therapy, and so on, can be combined with nanotechnology in clinic. Careful design/selection/synthesis of multifunctional imaging/therapeutic nanomaterials with therapeutic agents will be critical for the translational optimization these new image guided medicine techniques.

The intent of this Special Issue is to collect cutting-edge image-guided nanomedicine technology of leading scientists for providing a new opportunity and perspectives of the nanotechnology.

This Special Issue is intended to cover the following topics, but is not limited to them:

Multifunctional Imaging and Therapeutic Micro/Nano Carriers
New Interventional Approaches using nanomaterials
Smart Nanomaterials for Biomedical Applications
Noble metallic nanoparticles for Image Guided Medicine
Magnetic Nanoparticles Mediated Local Image Guided Therapy
Multifunctional Drug Delivery Carriers
Nano Radiosensitizers for Brachytherapy
Stimuli Responsive Polymeric Materials for Photodynamic/Photothermal Ablation

Any works concerning the imaging and nano for medical application, as well the development of new image-guided medicine approaches for the treatment of diseases, will be within the scope of this Special Issue. All submitted papers must present novel results, or the advancement of previously published data, and the matter should be dealt with scientific rigor.

Assist. Prof. Dong-Hyun Kim
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Imaging is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

Image guided therapy
Multimodal Medical Imaging
Translational Nano cancer therapeutics
Medical Imaging Contrast Agent
Nanotechnology
Organic/Inorganic/Metal Nano materials for Medicine
Cancer Treatment
Multifunctional Nano Platform
Thermo-responsive Polymer
Magnetic Hybrid Nanoparticles
Targeted Local Immuno-therapy

Published Papers (2 papers)

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Research

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759 KiB

Open AccessArticle

Towards a Novel Approach for Tumor Volume Quantification

by Amina Kharbach, Benaissa Bellach, Mohammed Rahmoune, Mohammed Rahmoun and Hanane Hadj Kacem

J. Imaging 2017, 3(4), 41; https://doi.org/10.3390/jimaging3040041 - 27 Sep 2017

Cited by 1 | Viewed by 3623

Abstract

In medical image processing, evaluating the variations of lesion volume plays a major role in many medical applications. It helps radiologists to follow-up with patients and examine the effects of therapy. Several approaches have been proposed to meet with medical expectations. The present work comes within this context. We present a new approach based on the local dissimilarity volume (LDV) that is a 3D representation of the local dissimilarity map (LDM). This map presents a useful means to compare two images, offering a localization of information. We proved the effectiveness of this method (LDV) compared to medical techniques used by radiologists. The result of simulations shows that we can quantify lesion volume by using the LDV method, which is an efficient way to calculate and localize the volume variation of anomalies. It allowed a time savings with the compete satisfaction of an expert during the medical treatment. Full article

(This article belongs to the Special Issue Nanoparticles and Medical Imaging for Image Guided Medicine)

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Review

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7 pages, 613 KiB

Open AccessFeature PaperReview

Image-Guided Cancer Nanomedicine

by Dong-Hyun Kim

J. Imaging 2018, 4(1), 18; https://doi.org/10.3390/jimaging4010018 - 11 Jan 2018

Cited by 31 | Viewed by 7062

Abstract

Multifunctional nanoparticles with superior imaging properties and therapeutic effects have been extensively developed for the nanomedicine. However, tumor-intrinsic barriers and tumor heterogeneity have resulted in low in vivo therapeutic efficacy. The poor in vivo targeting efficiency in passive and active targeting of nano-therapeutics along with the toxicity of nanoparticles has been a major problem in nanomedicine. Recently, image-guided nanomedicine, which can deliver nanoparticles locally using non-invasive imaging and interventional oncology techniques, has been paid attention as a new opportunity of nanomedicine. This short review will discuss the existing challenges in nanomedicine and describe the prospects for future image-guided nanomedicine. Full article

(This article belongs to the Special Issue Nanoparticles and Medical Imaging for Image Guided Medicine)

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