Dear Colleagues,

Nucleosides are an intrinsic part of all organisms and are involved in key processes that maintain life. Therefore, their presence within marine species is not surprising and is, and has been, an area of interest. The fact that nucleoside derivatives have been approved for certain treatments provide evidence of the potential that derivatives containing nucleosides as backbone have in the biomedical field. Examples highlighting the relationship between purine/pyrimidine derivatives, the backbone of nucleobases in DNA and RNA, and marine resources include their isolation from various sources in the marine world and have been studied in different contexts, e.g., as synthons for drug derivatives, as drug leads, within natural product biodiversity, determination of bioactivity, or basic research.

The aim of this Special Issue is to deliver a forum that expands interest on this topic to researchers in various fields, and highlights the potential of marine nucleosides as a central piece with interdisciplinary applications. This issue will provide up to date reports around developments, applications, or any topic regarding marine nucleosides broadly, and their role in fields spanning from biology and biochemistry to organic and physical organic chemistry. This includes, but is not limited to, aspects of natural products containing nucleosides, i.e., their biosynthesis, isolation, characterization, or use as potential drug derivatives; total synthesis as well as synthetic efforts towards novel derivatives containing nucleosides; effectivity of drug-containing nucleosides; biophysical and photophysical properties; proposed biosynthetic pathways; overall biochemical properties; or effects on living systems. Review articles pertaining to this field are also welcomed.

Dr. Marino Resendiz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Natural product synthesis/isolation/characterization/biosynthesis
• biological activity of products derived from marine nucleosides
• marine nucleosides as backbone of derivatives with interesting properties
• chemical/photochemical/biological reactivity of marine nucleosides and their derivatives