Lipidomics Volume 2

Dear Colleagues,

Lipids play diverse roles in biological systems: In addition to storing energy, they also act as structural scaffolds, modulators of membrane transport, and as signal transduction messengers. Increasing evidence from structural biology has established that detailed knowledge of lipid molecular structure is often required to fully appreciate the biochemical role of individual lipids.

Lipidomics, the comprehensive analysis of the lipid composition in a cell or tissue, has been driven by advances in analytical capabilities. These advances have been enabled primarily by mass spectrometry, a powerful tool for structural characterisation of lipids in biological samples. Methods for quantitative lipid analysis and detailed structural identification of unknown lipids are now well established. Contemporary instrumentation demonstrates ever-increasing sensitivity and resolution necessary for analysis of lipids in complex biological samples. Nevertheless, techniques complementary to mass spectrometry are highly valuable and have a role to play in lipid analysis. Furthermore, the ever-increasing complexity of data generated during lipidome analysis has required the development of novel tools for data analysis and feature mining in such datasets.

This Special Issue of Metabolites will be dedicated to the development of novel methods to characterize lipid structure, high-throughput lipidomics, characterization of lipid-protein interactions, clinical applications of lipidomics, and bioinformatic tools for analyzing large lipidomic datasets.

Dr. Simon H. J. Brown
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• lipidomics
• lipid metabolism
• lipid profiling
• global profiling of lipids
• metabolic phenotype
• lipid biomarkers
• lipid-protein interactions
• membranes
• mass spectrometry
• high resolution
• untargeted lipidomics
• targeted lipidomics
• data mining
• databases
• clinical lipidomics