Journal Browser

► Journal Browser

Special Issue Editor

Special Issue Information

Dear Colleagues,

The global population, and the need to generate enough food to feed everyone, continues to rise. At the same time, globalization and ecological pressures have increased the emergence of novel infections and pandemics in farmed animals. According to the World Health Organization, three new diseases emerge each year, two of which originate in livestock and 75% of which are zoonotic. These diseases affect livestock and the people who care for them. The lack of reliable and cost-effective diagnostic tests, devices, and instruments for early disease detection threatens to derail disease control efforts. Nanobiotechnology enabled by nanomaterials offers great promise as a potential solution to this problem; it can be used to create efficient and cost-effective diagnostic solutions for early disease detection in animals and food products, contributing to global long-term societal and economic health. In this Special Issue, we discuss the design, development, and testing of devices, micromachines, sensing tools, and instruments with end applications in food processing, sustainable food engineering, food safety, agriculture, and animal health. We look forward to the contributions from universities, research centres and institutions, government research labs, as well as academic and industrial organizations that will attempt to solve the grand challenges in the food, agricultural and biomedical sector.

Dr. Suresh Neethirajan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

Bioinstrumentation
Biosensors
Biomedical micro devices
Nanosensors
Medical devices
Point-of-care platforms

Published Papers (2 papers)

Download All Papers

Research

Jump to: Review

13 pages, 2661 KiB

Open AccessArticle

Detection of Hepatitis C Virus Core Protein in Serum Using Aptamer-Functionalized AFM Chips

by Tatyana O. Pleshakova, Anna L. Kaysheva, Ivan D. Shumov, Vadim S. Ziborov, Jana M. Bayzyanova, Vladimir A. Konev, Vasiliy F. Uchaikin, Alexander I. Archakov and Yuri D. Ivanov

Micromachines 2019, 10(2), 129; https://doi.org/10.3390/mi10020129 - 15 Feb 2019

Cited by 41 | Viewed by 4117

Abstract

In the present study, we demonstrate atomic force microscopy (AFM)-based detection of hepatitis C virus (HCV) particles in serum samples using a chip with aptamer-functionalized surface (apta-based AFM chip). The target particles, containing core antigen of HCV (HCVcoreAg protein), were biospecifically captured onto the chip surface from 1 mL of test solution containing 10 µL of serum collected from a hepatitis C patient. The registration of aptamer/antigen complexes on the chip surface was performed by AFM. The aptamers used in the present study were initially developed for therapeutic purposes; herein, these aptamers have been successfully utilized as probe molecules for HCVcoreAg detection in the presence of a complex protein matrix (human serum). The results obtained herein can be used for the development of detection systems that employ affine enrichment for protein detection. Full article

(This article belongs to the Special Issue Nanomaterials-Based Devices for Food, Agricultural, and Biomedical Applications)

► Show Figures

Figure 1

Review

Jump to: Research

17 pages, 3307 KiB

Open AccessReview

Recent Advances in AIV Biosensors Composed of Nanobio Hybrid Material

by Taek Lee, Jae-Hyuk Ahn, Sun Yong Park, Ga-Hyeon Kim, Jeonghyun Kim, Tae-Hyung Kim, Inho Nam, Chulhwan Park and Min-Ho Lee

Micromachines 2018, 9(12), 651; https://doi.org/10.3390/mi9120651 - 09 Dec 2018

Cited by 27 | Viewed by 5615

Abstract

Since the beginning of the 2000s, globalization has accelerated because of the development of transportation systems that allow for human and material exchanges throughout the world. However, this globalization has brought with it the rise of various pathogenic viral agents, such as Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), Zika virus, and Dengue virus. In particular, avian influenza virus (AIV) is highly infectious and causes economic, health, ethnical, and social problems to human beings, which has necessitated the development of an ultrasensitive and selective rapid-detection system of AIV. To prevent the damage associated with the spread of AIV, early detection and adequate treatment of AIV is key. There are traditional techniques that have been used to detect AIV in chickens, ducks, humans, and other living organisms. However, the development of a technique that allows for the more rapid diagnosis of AIV is still necessary. To achieve this goal, the present article reviews the use of an AIV biosensor employing nanobio hybrid materials to enhance the sensitivity and selectivity of the technique while also reducing the detection time and high-throughput process time. This review mainly focused on four techniques: the electrochemical detection system, electrical detection method, optical detection methods based on localized surface plasmon resonance, and fluorescence. Full article

(This article belongs to the Special Issue Nanomaterials-Based Devices for Food, Agricultural, and Biomedical Applications)

► Show Figures