Special Issue "Nutrigenetics and Nutrigenomics"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (31 August 2012)
Dr. Catherine Phillips
HRB Centre for Diet and Health Research, Department of Epidemiology and Public Health, University College Cork, Ireland and School of Public Health, Physiotherapy and Sports Science, University College Dublin, Ireland
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Interests: dietary and lifestyle determinants of metabolically healthy obesity; nutrigenetics; metabolic syndrome; nutritional and genetic epidemiology in the context of maternal; childhood, adult and intergenerational obesity; metabolic health and disease
An individual's phenotype represents a complex interaction between the genetic and environmental factors over their lifetime. Nutrition is a key environmental factor in the pathogenesis and progression of common polygenic, diet-related cardiometabolic diseases such as obesity, metabolic syndrome, diabetes and cardiovascular disease. Nutrigenomics and nutrigenetics are rapidly emerging multidisciplinary sciences, which aim to explore the effects of nutrients on the genome, proteome and metabolome, and to elucidate the effect of genetic variation on the interaction between diet and disease. Nutrigenetics has the potential to change the future of dietary guidelines and diet-related disease prevention and therapy. A personalised nutrition approach based on identification of nutrient sensitive or responsive genotypes, whereby nutrient intake is manipulated or optimised based on an individuals' genetic profile to reduce disease risk or improve effectiveness of dietary recommendations, offers the potential to break the traditional public health "one size fits all" approach.
This special issue will highlight emerging research which contributes to our understanding of the role of nutrigenetics and/or nutrigenomics in the development, prevention and treatment of disease. Both research articles and reviews which explore these topics across a wide spectrum of diseases/phenotypes and research activity; from cellular and animal models, through to human studies and epidemiology are welcome.
Dr. Catherine Phillips
- gene-environment interactions
- personalised nutrition
- nutrient responsive genotypes
- metabolic syndrome