Special Issue "Current Trends in Dosage Form Development"

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A special issue of Pharmaceutics (ISSN 1999-4923).

Deadline for manuscript submissions: closed (31 December 2010)

Special Issue Editor

Guest Editor
Prof. Dr. Roderick B. Walker

Faculty of Pharmacy, Rhodes University, Grahamstown, 6140, South Africa
E-Mail
Fax: + 27 (46) 636 1205
Interests: sustained release matrices; dissolution testing; formulation; paediatric formulation; biopharmaceutics; nanotechnology

Special Issue Information

This issue focuses on current approaches and trends in the development, formulation, manufacture and assessment of dosage forms.

Keywords

  • formulation
  • drug delivery
  • novel approaches to solving formulation issues
  • scale-up
  • manufacture
  • dosage form development

Published Papers (1 paper)

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Research

Open AccessArticle Effect of Moisture on Powder Flow Properties of Theophylline
Pharmaceutics 2010, 2(3), 275-290; doi:10.3390/pharmaceutics2030275
Received: 19 May 2010 / Revised: 24 June 2010 / Accepted: 30 June 2010 / Published: 2 July 2010
Cited by 9 | PDF Full-text (1672 KB) | HTML Full-text | XML Full-text
Abstract
Powder flow is influenced by environmental factors, such as moisture and static electricity, as well as powder related factors, such as morphology, size, size distribution, density, and surface area. Pharmaceutical solids may be exposed to water during storage in an atmosphere containing water
[...] Read more.
Powder flow is influenced by environmental factors, such as moisture and static electricity, as well as powder related factors, such as morphology, size, size distribution, density, and surface area. Pharmaceutical solids may be exposed to water during storage in an atmosphere containing water vapor, or in a dosage form consisting of materials (e.g., excipients) that contain water and are capable of transferring in to other ingredients. The effect of moisture on powder flowability depends on the amount of water and its distribution. The aim of this work was to examine the effect of humidity on the flow properties of theophylline using information derived from solid-state analysis of the systems investigated. Full article
(This article belongs to the Special Issue Current Trends in Dosage Form Development)
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