Atmospheric Pressure Plasma Sources Applied in Biological Systems

A special issue of Plasma (ISSN 2571-6182).

Deadline for manuscript submissions: closed (28 February 2019) | Viewed by 9503

Special Issue Editor


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Guest Editor
Radiation Laboratory and Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN 46556, USA
Interests: ambient pressure and ultra high vacuum X-ray photoelectron spectroscopy; atmospheric pressure plasma jets; dissociative electron attachment to gas-phase molecules

Special Issue Information

Dear Colleagues,

Recent advances in plasma technology have realized the utilization of atmospheric pressure plasma sources for biotechnological applications, including agriculture, food production and medicine. Atmospheric pressure plasmas are ignited during electric discharges under gaseous atmospheric conditions, which produce a variety of plasma components such as photons, electrons, excited ions, ionic and neutral radicals, and electromagnetic fields. The reactive species, such as reactive oxygen species and reactive nitrogen species from the plasma, are believed to be mainly involved in a number of cellular and biomolecular processes. However, the synergistic effect of all plasma components has been shown to result in unexpected consequences; thus current plasma research seeks a deeper fundamental understanding of plasma complexity as well as the development of a variety of plasma sources.

The aim of this Special Issue is to collect and give visibility to the latest experimental, theoretical, and computational results that enhance the understanding of physical, chemical, and biological mechanisms underlying plasma-biological system interactions, ultimately leading to achieve an effective and reliable plasma technology.

Submissions are invited on topics including, but not limited to:

  • Development and characterization of atmospheric pressure plasma devices
  • Plasma-induced effects on living systems and organisms, as well as isolated biomolecules
  • Plasma tissue engineering
  • Methods for designing and optimizing desired biochemical processes and outcomes
  • Models of plasma-biological systems
  • Atmospheric pressure plasma in cancer treatment and other medical applications
  • In situ diagnostics of physical and biochemical responses to plasma treatment

Prof. Dr. Sylwia Ptasinska
Guest Editor

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Keywords

  • Atmospheric pressure plasmas
  • plasma medicine
  • plasma biotechnology
  • plasma physics and chemistry

Published Papers (2 papers)

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Research

12 pages, 19397 KiB  
Article
On the Electrical and Optical Features of the Plasma Coagulation Controller Low Temperature Atmospheric Plasma Jet
by Luigi Cordaro, Gianluca De Masi, Alessandro Fassina, Davide Mancini, Roberto Cavazzana, Daniele Desideri, Piergiorgio Sonato, Matteo Zuin, Barbara Zaniol and Emilio Martines
Plasma 2019, 2(2), 156-167; https://doi.org/10.3390/plasma2020012 - 04 May 2019
Cited by 7 | Viewed by 4408
Abstract
We report on the electrical and optical characterization of the Plasma Coagulation Controller (PCC) device, a low temperature atmospheric plasma source for biomedical applications. This device, designed for the study of plasma-induced blood coagulation, has been developed to operate flexibly in several operational [...] Read more.
We report on the electrical and optical characterization of the Plasma Coagulation Controller (PCC) device, a low temperature atmospheric plasma source for biomedical applications. This device, designed for the study of plasma-induced blood coagulation, has been developed to operate flexibly in several operational conditions, since it is possible to vary the applied voltage V p and the pulse repetition rate f in a quite wide range ( V p range: 2–12 kV, f range: 1–40 kHz). Emission spectroscopy measurements were conducted by varying the line of sight along the axis of helium and neon plasma plumes. The increase of the Reactive Oxygen and Nitrogen Species (RONS) has been observed, as one moves from inside the gas pipe to the outside, as a consequence of the gas mixture with the surrounding air. Furthermore, high-speed photographs of the plasma jet were taken, showing that the plasma is not uniformly distributed in a continuous volumetric region, the plasma being concentrated in localized structures called Pulsed Atmospheric-pressure Plasma Streams (PAPS). The propagation velocities of these objects have been examined, noting that they are not related to the propagation of ion sound waves. Rather, we provide indications that the streamer propagation speed is proportional to the electron drift velocity. Full article
(This article belongs to the Special Issue Atmospheric Pressure Plasma Sources Applied in Biological Systems)
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14 pages, 4298 KiB  
Article
Acinetobacter baumannii Deactivation by Means of DBD-Based Helium Plasma Jet
by Panagiotis Svarnas, Anastasia Spiliopoulou, Petros G. Koutsoukos, Kristaq Gazeli and Evangelos D. Anastassiou
Plasma 2019, 2(2), 77-90; https://doi.org/10.3390/plasma2020008 - 03 Apr 2019
Cited by 22 | Viewed by 4552
Abstract
Acinetobacter baumannii is a typically short, almost round, rod-shaped (coccobacillus) Gram-negative bacterium. It can be an opportunistic pathogen in humans, affecting people with compromised immune systems, and it is becoming increasingly important as a hospital-associated (nosocomial) infection. It has also been isolated from [...] Read more.
Acinetobacter baumannii is a typically short, almost round, rod-shaped (coccobacillus) Gram-negative bacterium. It can be an opportunistic pathogen in humans, affecting people with compromised immune systems, and it is becoming increasingly important as a hospital-associated (nosocomial) infection. It has also been isolated from environmental soil and water samples. In this work, unlike conventional medical methods like antibiotics, the influence of atmospheric-pressure cold plasma on this bacterium is evaluated by means of a colony count technique and scanning electron microscopy. The plasma used here refers to streamers axially propagating into a helium channel penetrating the atmospheric air. The plasma is probed with high resolution optical emission spectroscopy and copious reactive species are unveiled under low-temperature conditions. Based on the experimental results, post-treatment (delayed) biochemical effects on Acinetobacter baumannii and morphological modifications appear dominant, leading to complete deactivation of this bacterium. Full article
(This article belongs to the Special Issue Atmospheric Pressure Plasma Sources Applied in Biological Systems)
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