Special Issue "Immunosensors 2014"
Deadline for manuscript submissions: closed (31 March 2015)
Dr. Jo V. Rushworth (Website)
LIGHT Laboratories, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK
Interests: biosensors; impedance; biochemistry; synthetic bioreceptors; Alzheimer’s disease; amyloid-beta
Prof. Dr. Paul A. Millner (Website)
Professor of Bionanotechnology and Head of School, LIGHT Laboratories, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK
Interests: bionanotechnology; biosensors; electrochemistry; impedance; photo-remediation; nanoparticles; nanofibres.
Antibodies are employed as bioreceptors in a wide range of biosensing devices, including electrochemical, optical and mechanical sensors, as well as immunoassays and ELISAs. Antibodies facilitate highly specific and sensitive analyte detection by virtue of the high-affinity antibody-antigen interaction. Immunosensors utilize antibodies, or fragments of antibodies, to transduce analyte binding into a measurable signal based on several methods, including generation of (i) an optical signal from a colored product or fluorescent signal, (ii) an electrochemical signal or (iii) a mechanical readout. Immunosensors have been developed for various applications, including medical diagnostics, environmental monitoring and public health and safety applications. These technologies allow for portable, rapid and cost-effective analyte detection and monitoring, which can be performed in the field without the need for specialist users or costly lab equipment.
Recently, efforts are focussed on several areas in order to improve immunosensor performance and to encourage commercialisation of laboratory-based technologies. These include bioreceptor orientation and antibody engineering, transducer surface nano-modification, device miniaturisation and integration with microfluidic platforms. Furthermore, label-free immunosensors present the advantages of reduced costs and ease of operation without the need for sample pre-treatment.
We are delighted to invite you to submit both original research papers and review articles relating to the application of antibodies, or their derivatives, to biosensing devices.
Dr. Jo V. Rushworth
Prof. Dr. Paul A. Millner
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.
- bioreceptor immobilisation/orientation
- transducer nano-modification
- optical biosensing
- quartz crystal microbalance (QCM)
- surface plasmon resonance (SPR)