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Microfluidic Sensors 2018
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Microfluidic Sensors 2018

A special issue of Sensors (ISSN 1424-8220).

Deadline for manuscript submissions: closed (28 February 2019) | Viewed by 23240

Special Issue Editors

Dr. Romeo Bernini

E-Mail Website
Guest Editor
Institute for Electromagnetic Sensing of the Environment, 80124 Napoli, Italy
Interests: integrated optical sensors; optical fiber sensors; distributed fiber sensors; lab-on-chip; optical resonator; sensors for biomedical application
Special Issues, Collections and Topics in MDPI journals
Dr. Genni Testa

E-Mail Website
Guest Editor
Institute for Electromagnetic Sensing of the Environment, 80124 Napoli, Italy
Interests: integrated optical sensors; interferometric waveguide sensors; resonator waveguide sensors; sensors for biomedical application
Special Issues, Collections and Topics in MDPI journals
Dr. Gianluca Persichetti

E-Mail Website
Guest Editor
Institute for Electromagnetic Sensing of the Environment, 80124 Napoli, Italy
Interests: optical fiber sensors; optical waveguides for sensing applications; optical waveguides sensor fabrication techniques; optical lab-on-chip sensors; polymer optical fiber/waveguide sensors; specialty fibers for sensing applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The integration between sensors and microfluidics is a rapidly developing research area with application implications in health, environmental monitoring, food, and chemical and biological analysis.

This Special Issue aims to cover advancements, developments and applications over a wide range of topics in this area. We solicit research papers as well as state-of-the-art contributions and critical reviews.

This Special Issue aims at providing an overview of a wide class of sensors integrated with microfluidics (optical, acoustic, electrical, electrochemical, mechanical, etc.) and their use to generate complex and operative microsystems for several applications (biomedical, chemistry, environmental, etc.)

Dr. Romeo Bernini
Dr. Genni Testa
Dr. Gianluca Persochetti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sensors
  • microfluidics
  • smart materials
  • sensing materials
  • paper microfluidic
  • integration
  • detection in microfluidics
  • Lab-on-a-chip
  • Point-of-Care
  • centrifugal microfluidic
  • droplet microfluidics
  • integrated devices
  • micro-TAS
  • optofluidics
  • single cell sensing

Published Papers (4 papers)

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Research

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18 pages, 7310 KiB  
Article
Novel Cost-Effective Microfluidic Chip Based on Hybrid Fabrication and Its Comprehensive Characterization
by Sanja P. Kojic, Goran M. Stojanovic and Vasa Radonic
Sensors 2019, 19(7), 1719; https://doi.org/10.3390/s19071719 - 10 Apr 2019
Cited by 24 | Viewed by 6969
Abstract
Microfluidics, one of the most attractive and fastest developed areas of modern science and technology, has found a number of applications in medicine, biology and chemistry. To address advanced designing challenges of the microfluidic devices, the research is mainly focused on development of [...] Read more.
Microfluidics, one of the most attractive and fastest developed areas of modern science and technology, has found a number of applications in medicine, biology and chemistry. To address advanced designing challenges of the microfluidic devices, the research is mainly focused on development of efficient, low-cost and rapid fabrication technology with the wide range of applications. For the first time, this paper presents fabrication of microfluidic chips using hybrid fabrication technology—a grouping of the PVC (polyvinyl chloride) foils and the LTCC (Low Temperature Co-fired Ceramics) Ceram Tape using a combination of a cost-effective xurography technique and a laser micromachining process. Optical and dielectric properties were determined for the fabricated microfluidic chips. A mechanical characterization of the Ceram Tape, as a middle layer in its non-baked condition, has been performed and Young’s modulus and hardness were determined. The obtained results confirm a good potential of the proposed technology for rapid fabrication of low-cost microfluidic chips with high reliability and reproducibility. The conducted microfluidic tests demonstrated that presented microfluidic chips can resist 3000 times higher flow rates than the chips manufactured using standard xurography technique. Full article
(This article belongs to the Special Issue Microfluidic Sensors 2018)
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11 pages, 7060 KiB  
Article
An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
by Yongyuan Liang, Mingsheng Ma, Faqiang Zhang, Feng Liu, Zhifu Liu, Dong Wang and Yongxiang Li
Sensors 2019, 19(5), 1189; https://doi.org/10.3390/s19051189 - 08 Mar 2019
Cited by 27 | Viewed by 4802
Abstract
This work reports a novel wireless microfluidic biosensor based on low temperature co-fired ceramic (LTCC) technology. The wireless biosensor consists of a planar spiral inductor and parallel plate capacitor (LC) resonant antenna, which integrates with microchannel bends in the LTCC substrate. The wireless [...] Read more.
This work reports a novel wireless microfluidic biosensor based on low temperature co-fired ceramic (LTCC) technology. The wireless biosensor consists of a planar spiral inductor and parallel plate capacitor (LC) resonant antenna, which integrates with microchannel bends in the LTCC substrate. The wireless response of the biosensor was associated to the changes of its resonant frequency due to the alteration in the permittivity of the liquid flow in the microchannel. The wireless sensing performance to different organic liquids with permittivity from 3 to 78.5 was presented. The measured results are in good agreement with the theoretical calculation. The wireless detection for the concentration of glucose in water solution was investigated, and an excellent linear response and repeatability were obtained. This kind of LC wireless microfluidic sensor is very promising in establishing wireless lab-on-a-chip for biomedical and chemical applications. Full article
(This article belongs to the Special Issue Microfluidic Sensors 2018)
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9 pages, 2196 KiB  
Article
Planar Inverted-F Antenna (PIFA) Using Microfluidic Impedance Tuner
by Minjae Lee and Sungjoon Lim
Sensors 2018, 18(10), 3176; https://doi.org/10.3390/s18103176 - 20 Sep 2018
Cited by 11 | Viewed by 5325
Abstract
This paper proposes a microfluidic impedance tuner that is applied to a planar inverted-F antenna (PIFA). The proposed microfluidic impedance tuner is designed while using a simple double-stub and the impedance is changed by tuning the stub length. In this work, the stub [...] Read more.
This paper proposes a microfluidic impedance tuner that is applied to a planar inverted-F antenna (PIFA). The proposed microfluidic impedance tuner is designed while using a simple double-stub and the impedance is changed by tuning the stub length. In this work, the stub length can be tuned by injecting a liquid metal alloy to the microfluidic channels. Initially, the PIFA operates at 900 MHz with impedance matching of 50 Ω. The impedance is mismatched when a hand is placed close to the antenna. The mismatched impedance is matched to 50 Ω by injecting the liquid metal alloy. The antenna is fabricated on the FR-4 substrate, and the impedance tuner is fabricated on polydimethylsiloxane (PDMS). In order to inject the liquid metal alloy, a piezoelectric micropump and microprocessor are used in the measurement. At 900 MHz, the return loss is successfully tuned from 4.69 dB to 18.4 dB when a hand is placed 1 mm above the antenna. Full article
(This article belongs to the Special Issue Microfluidic Sensors 2018)
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Review

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17 pages, 1993 KiB  
Review
Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
by Boon Kar Yap, Siti Nur’Arifah M.Soair, Noor Azrina Talik, Wai Feng Lim and Lai Mei I
Sensors 2018, 18(8), 2625; https://doi.org/10.3390/s18082625 - 10 Aug 2018
Cited by 9 | Viewed by 5535
Abstract
Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia [...] Read more.
Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection. Full article
(This article belongs to the Special Issue Microfluidic Sensors 2018)
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