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Fiber Optic Sensors for Smart Catheters

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 July 2018) | Viewed by 12000

Special Issue Editors


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Guest Editor
Optical Fibre Sensors Research Centre (OFSRC), University of Limerick, Limerick V94 T9PX, Ireland
Interests: optical fibre sensors; medical sensors; optical fibre instrumentation
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Optoelectronic Group, Department of Engineering, University of Sannio, Corso Garibaldi 107, Benevento, Italy
Interests: nanobiophotonics; fiber optic nanoprobes; optical biosensors; plasmonics; lab-on-fiber, lab-in-a-needle
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
National Engineering Laboratory for Fiber Optic Sensing Technology, Wuhan University of Technology, Wuhan 430070, China
Interests: Fiber Optic Sensors; sensing materials; sensor aplications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Medical Catheters are well established and ubiquitous in modern clinical practice. Optical Fibre Sensor (OFS) technology for medical sensors is a rapidly-growing field of research, which lends itself well for use within catheters for making a wide range of medical and/or biomedical pressure. OFS have many attractive features which allow them to be effectively deployed as sensors within existing and purpose designed novel medical catheters. These include miniaturization, immunity to external electromagnetic radiation, e.g., in the case of Magnetic Resonance Imaging and other imaging/scanning systems, their ability to be functionalised, and specific performance advantages such as capability for rapid response, high sensitivity coupled with specificity, especially as chemical and/or physical sensors in biological sensing.

The concept of the ‘Smart Catheter’ approach is designed to transform conventional catheters and optical fibre sensors into a robust technology which is ideally suited for undertaking a wide range of in vivo real time medical measurements. The Optical Fibre Sensing approach means that the light signal interaction with its environment can take place at the tip of the fibre or along an extended surface in the sensor location e.g. by evanescent wave interaction. The broad approach to sensing means that several different parameters can be measured covering a wide range of clinical applications.

Specifically, Smart Catheter technology platforms can be subdivided in three main classes:

– Single point sensor within catheter;

– Quasi-Distributed or multi-point sensor within a catheter;

– Modified catheter coupled with the sensor. In this case, the catheter itself has been modified or designed from scratch to play an important role in coupling the measurand signal to the sensor.

This Special Issue is proposed to collect invited manuscripts written by the leading authorities in the field. Specifically, with special focus on chemical and biological sensing applications, this Issue will include both research and review papers dealing with:

- successful development and/or demonstration of novel Smart Catheter based sensing systems;

- integration of Smart Catheter with existing medical systems;

- Advancements in materials for use in Smart Catheters e.g. coatings for improved performance;

- emerging methodologies for fabrication methods feature placement on Smart Catheters, e.g., using femto-second laser based systems.

Prof. Dr. Elfed Lewis
Prof. Dr. Andrea Cusano
Prof. Dr. Minghong Yang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Optical Fibre Sensors
  • Medical Catheters
  • Nanophotonics
  • Plasmonics
  • SERS
  • Metamaterials
  • Label free sensing
  • Laser Etching
  • Chemical Etching
  • Biosensing
  • Multimaterial Optical Fibers
  • Lab in a Needle
  • Biomedical Devices

Published Papers (2 papers)

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Research

11 pages, 1514 KiB  
Article
Double Assurance of Epidural Space Detection Using Fiberoptics-Based Needle Design and Autofluorescence Technologies for Epidural Blockade in Painless Labor
by Cihun-Siyong Alex Gong, Huang-Chang Lee, Yin Chang, Chien-Kun Ting and Po-Hsun Tu
Sensors 2018, 18(11), 3592; https://doi.org/10.3390/s18113592 - 23 Oct 2018
Cited by 1 | Viewed by 2751
Abstract
Purpose: Technology of reflectance spectroscopy incorporated with auto-fluorescence spectroscopy were employed to increase the safety of epidural placement in regional anesthesia which is generally used for surgery, epidural anesthesia, post-operative pain control and painless childbirth. Method: Ex vivo study of auto-fluorescence spectroscopy was [...] Read more.
Purpose: Technology of reflectance spectroscopy incorporated with auto-fluorescence spectroscopy were employed to increase the safety of epidural placement in regional anesthesia which is generally used for surgery, epidural anesthesia, post-operative pain control and painless childbirth. Method: Ex vivo study of auto-fluorescence spectroscopy was performed for the para-vertebral tissues contained fat, interspinous ligament, supraspinous ligament and ligamentumflavum by multimode microplate reader at wavelength 405 nm for the purpose of tissue differentiation. A specially designed optic-fiber-embedded needle was employed to incorporate with both reflectance and autofluorescence spectroscopies in order to probe the epidural space as double assurance demands. In vivo study was carried out in a Chinese native swine weighted about 30 kg under intubated general anesthesia with ventilation support. The reflective (405 nm) and autofluorescence signals (λ and λ*) were recorded at 5 different sites by an oscilloscope during the needle puncture procedure from skin to epidural space in the back of the swine. Results: Study of either autofluorescence spectroscopy for tissue samples or ex vivo needle puncture in porcine trunk tissues indicates that ligmentumflavum has at least 10-fold higher fluorescence intensity than the other tissues. In the in vivo study, ligamentumflavum shows a double-peak character for both reflectance and autofluorescence signals. The epidural space is located right after the drop from the double-peak. Both peaks of reflectance and fluorescence are coincident which ensures that the epidural space is correctly detected. Conclusions: The fiber-optical technologies of double-assurance demands for tissue discrimination during epidural needle puncture can not only provide an objective visual information in a real-time fashion but also it can help the operator to achieve much higher success rate in this anesthesia procedure. Full article
(This article belongs to the Special Issue Fiber Optic Sensors for Smart Catheters)
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9 pages, 2814 KiB  
Article
Smart Optical Catheters for Epidurals
by Benito Carotenuto, Armando Ricciardi, Alberto Micco, Ezio Amorizzo, Marco Mercieri, Antonello Cutolo and Andrea Cusano
Sensors 2018, 18(7), 2101; https://doi.org/10.3390/s18072101 - 30 Jun 2018
Cited by 20 | Viewed by 8204
Abstract
Placing the needle inside the epidural space for locoregional anesthesia is a challenging procedure, which even today is left to the expertise of the operator. Recently, we have demonstrated that the use of optically sensorized needles significantly improves the effectiveness of this procedure. [...] Read more.
Placing the needle inside the epidural space for locoregional anesthesia is a challenging procedure, which even today is left to the expertise of the operator. Recently, we have demonstrated that the use of optically sensorized needles significantly improves the effectiveness of this procedure. Here, we propose an optimized configuration, where the optical fiber strain sensor is directly integrated inside the epidural catheter. The new design allows the solving of the biocompatibility issues and increases the versatility of the former configuration. Through an in vivo study carried out on a porcine model, we confirm the reliability of our approach, which also opens the way to catheter monitoring during insertion inside biological spaces. Full article
(This article belongs to the Special Issue Fiber Optic Sensors for Smart Catheters)
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