Synthesis and Antifungal Activity of Carabrone Derivatives
Abstract
:1. Introduction
2. Results and Discussion
Compd. | Regression equation (Y = a + bX) | r | EC50b (μg/mL) | EC50 95% CL/(μg/mL) |
---|---|---|---|---|
1 | Y = 3.6090 + 1.6337X | 0.9974 | 7.10 | 6.19~8.02 |
6 | Y = 4.5130 + 1.3891X | 0.9923 | 2.24 | 1.97~2.55 |
7 | Y = 3.4038 + 2.5118X | 0.9817 | 4.32 | 3.81~4.85 |
8 | Y = 4.3577 + 1.3351X | 0.9979 | 3.03 | 2.58~3.55 |
9 | Y = 3.1867 + 1.0358X | 0.9942 | 56.30 | 42.95~73.80 |
10 | Y = 3.2442 + 1.1736X | 0.9969 | 31.34 | 26.08~37.66 |
11 | Y = 4.2780 + 0.6720X | 0.9882 | 10.78 | 9.16~12.68 |
12 | Y = 4.3568 + 0.7209X | 0.9920 | 6.39 | 5.33~7.65 |
13 | Y = 3.7775 + 0.9365X | 0.9970 | 20.20 | 16.85~24.22 |
14 | Y = 3.7676 + 1.0011X | 0.9962 | 17.02 | 14.41~20.11 |
chlorothalonil c | Y = 5.1247 + 1.0081X | 0.9935 | 0.75 | 0.63~0.90 |
3. Experimental
3.1. General
3.2. Synthesis
General procedure for the synthesis of compounds 11-14 [20]
3.3. Spore Germination Assay
4. Conclusions
Acknowledgements
- Sample Availability: Samples of the compounds are available from the authors.
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Feng, J.-T.; Ma, Z.-Q.; Li, J.-H.; He, J.; Xu, H.; Zhang, X. Synthesis and Antifungal Activity of Carabrone Derivatives. Molecules 2010, 15, 6485-6492. https://doi.org/10.3390/molecules15096485
Feng J-T, Ma Z-Q, Li J-H, He J, Xu H, Zhang X. Synthesis and Antifungal Activity of Carabrone Derivatives. Molecules. 2010; 15(9):6485-6492. https://doi.org/10.3390/molecules15096485
Chicago/Turabian StyleFeng, Jun-Tao, Zhi-Qing Ma, Jiang-Hua Li, Jun He, Hui Xu, and Xing Zhang. 2010. "Synthesis and Antifungal Activity of Carabrone Derivatives" Molecules 15, no. 9: 6485-6492. https://doi.org/10.3390/molecules15096485