Shorter P1m Response in Children with Autism Spectrum Disorder without Intellectual Disabilities
Abstract
:1. Introduction
2. Results
2.1. P1m Latency and Intensity
2.2. Correlation between P1m Latency and Language-Related Performances
2.3. Correlation between P1m Intensity and Language-Related Performances
3. Discussion
4. Materials and Methods
4.1. Participants
4.2. Cognitive and Language Performance Measurements
4.3. Auditory Stimuli
4.4. Magnetoencephalography Recording
4.5. Data Analysis
4.6. Statistical Analysis
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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TD | ASD | t | p | |
---|---|---|---|---|
Latency (ms) | ||||
Left (N) | 38 | 26 | ||
108 (10.8) | 101 (13.0) | 2.390 | 0.020 * | |
Right (N) | 16 | 20 | ||
97 (18.9) | 98 (20.0) | −0.232 | 0.818 | |
Intensity (nAm) | ||||
Left (N) | 38 | 26 | ||
18.5 (6.5) | 18.4 (7.8) | 0.059 | 0.953 | |
Right (N) | 16 | 20 | ||
13.3 (5.0) | 15.2 (6.8) | −0.966 | 0.341 |
TD | ASD | |||
---|---|---|---|---|
r | p | r | p | |
Latency | ||||
Left | −0.157 | 0.346 | −0.471 | 0.015 * |
Right | 0.127 | 0.640 | −0.418 | 0.067 |
Intensity | ||||
Left | 0.205 | 0.217 | −0.102 | 0.619 |
Right | 0.523 | 0.038 | −0.333 | 0.151 |
TD | ASD | t | p | |
---|---|---|---|---|
Number of participants | 46 | 29 | ||
Gender (male/female) | 41/5 | 21/8 | n.s. | |
Chronological age (months) | 70.3 (63–91) | 74.7 (60–98) | n.s. | |
Handedness (right/left) | 42/4 | 27/2 | n.s. | |
K-ABC 1–MPS 2 | 104.7 (12.9) | 91.4 (11.7) | 4.488 | <0.001 |
K-ABC 1–AS 3 | 101.4 (13.9) | 95.2 (13.4) | 1.913 | n.s. |
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Yoshimura, Y.; Ikeda, T.; Hasegawa, C.; An, K.-M.; Tanaka, S.; Yaoi, K.; Iwasaki, S.; Saito, D.N.; Kumazaki, H.; Hiraishi, H.; et al. Shorter P1m Response in Children with Autism Spectrum Disorder without Intellectual Disabilities. Int. J. Mol. Sci. 2021, 22, 2611. https://doi.org/10.3390/ijms22052611
Yoshimura Y, Ikeda T, Hasegawa C, An K-M, Tanaka S, Yaoi K, Iwasaki S, Saito DN, Kumazaki H, Hiraishi H, et al. Shorter P1m Response in Children with Autism Spectrum Disorder without Intellectual Disabilities. International Journal of Molecular Sciences. 2021; 22(5):2611. https://doi.org/10.3390/ijms22052611
Chicago/Turabian StyleYoshimura, Yuko, Takashi Ikeda, Chiaki Hasegawa, Kyung-Min An, Sanae Tanaka, Ken Yaoi, Sumie Iwasaki, Daisuke N. Saito, Hirokazu Kumazaki, Hirotoshi Hiraishi, and et al. 2021. "Shorter P1m Response in Children with Autism Spectrum Disorder without Intellectual Disabilities" International Journal of Molecular Sciences 22, no. 5: 2611. https://doi.org/10.3390/ijms22052611