Information Encoded by the Flavivirus Genomes beyond the Nucleotide Sequence
Abstract
:1. Introduction
2. Structural Diversification of the Flavivirus RNA Genome
2.1. 5′ Untranslated Region
2.2. 3′ Untranslated Region
3. Cyclization of the Flavivirus Genome
4. Subgenomic Flavivirus RNAs
4.1. Biogenesis of sfRNAs
4.2. 3D xrRNA Folding Is Preserved across Flaviviruses
4.3. The Role of sfRNAs
4.4. xrRNAs in Other Viruses
5. Conclusions and Perspectives
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Name | Abbreviation |
---|---|
Mosquito-borneflaviviruses * | MBFV |
Dengue virus clade | DENV |
Dengue virus serotype 1 | DENV-1 |
Dengue virus serotype 1 | DENV-2 |
Dengue virus serotype 1 | DENV-3 |
Dengue virus serotype 1 | DENV-4 |
Japanese encephalitis virus clade | JEV clade |
Japanese encephalitis virus | JEV |
West Nile virus | WNV |
Spondweni virus clade | SPOV |
Zika virus | ZIKV |
Yellow fever virus clade | YFV clade |
Yellow fever virus | YFV |
Tick-borne flaviviruses * | TBFV |
Mammalian tick-borne virus | |
Tick-borne encephalitis virus | TBEV |
No-known-vector flaviviruses * | NKFV |
Modoc virus | MODV |
Insect-specific flaviviruses * | ISFV |
Classic insect-specific flavivirus clade | cISFV |
Cell fusion agent virus | CFAV |
Divergent Flaviviruses * | |
Tamana bat virus | TABV |
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Ramos-Lorente, S.; Romero-López, C.; Berzal-Herranz, A. Information Encoded by the Flavivirus Genomes beyond the Nucleotide Sequence. Int. J. Mol. Sci. 2021, 22, 3738. https://doi.org/10.3390/ijms22073738
Ramos-Lorente S, Romero-López C, Berzal-Herranz A. Information Encoded by the Flavivirus Genomes beyond the Nucleotide Sequence. International Journal of Molecular Sciences. 2021; 22(7):3738. https://doi.org/10.3390/ijms22073738
Chicago/Turabian StyleRamos-Lorente, Sara, Cristina Romero-López, and Alfredo Berzal-Herranz. 2021. "Information Encoded by the Flavivirus Genomes beyond the Nucleotide Sequence" International Journal of Molecular Sciences 22, no. 7: 3738. https://doi.org/10.3390/ijms22073738