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Review
Peer-Review Record

Intestinal Microbiota Interventions to Enhance Athletic Performance—A Review

Int. J. Mol. Sci. 2024, 25(18), 10076; https://doi.org/10.3390/ijms251810076
by Bharati Kadamb Patel 1, Kadamb Haribhai Patel 2, Chuen Neng Lee 1 and Shabbir Moochhala 1,3,*
Reviewer 1:
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2024, 25(18), 10076; https://doi.org/10.3390/ijms251810076
Submission received: 1 August 2024 / Revised: 17 September 2024 / Accepted: 18 September 2024 / Published: 19 September 2024
(This article belongs to the Special Issue Molecular Progression of Gut Microbiota)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

 

This review article covers an interesting area and is well written. I only have a few comments below.

 

Line 58-59: Additionally, there are around 2000 uncultured species in human GI tract.

https://www.nature.com/articles/s41586-019-0965-1

 

Section 3: regarding SCFA as an energy substrate for the body. The energy from SCFA is essentially from food, and the bacteria have utilized a portion of the energy for its own growth. In terms of host endurance, would it not be more energy efficient to not have the bacteria process the food and utilized by the host directly?

 

In Figure 4, there is primary one direction from microbiome to the muscle, not too much illustration on the muscle to microbiome direction.

 

Section 7: Diet seems to affect host endurance directly and not through microbiome. I would recommend reducing the content in this section to focus on the main point of the review.

 

Section 9: Please change subtitle to “potential” mode of action on an Athlete's Endurance.

 

Content on section 8 and 10 should be rearranged. I would suggest having a separate section for probiotics only, and another for prebiotics, synbiotics, etc.

 

All the references are not readable due to lack of space in between words.

Author Response

Please see attached file

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

Please see attached 

Comments for author File: Comments.pdf

Comments on the Quality of English Language

English language needs moderate editing.

Author Response

Please see attached file

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

Comments and Suggestions for Authors

The manuscript is ready for acceptance.

Author Response

Thank you very much for your valuable comments and suggestions.

Reviewer 2 Report

Comments and Suggestions for Authors

Please see the attachment

Comments for author File: Comments.pdf

Comments on the Quality of English Language

Minor English language changes required

Author Response

Please see attached file 16092024 Response to reviewer 2

Author Response File: Author Response.pdf

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