Intestinal Microbiota Interventions to Enhance Athletic Performance—A Review
Round 1
Reviewer 1 Report
Comments and Suggestions for Authors
This review article covers an interesting area and is well written. I only have a few comments below.
Line 58-59: Additionally, there are around 2000 uncultured species in human GI tract.
https://www.nature.com/articles/s41586-019-0965-1
Section 3: regarding SCFA as an energy substrate for the body. The energy from SCFA is essentially from food, and the bacteria have utilized a portion of the energy for its own growth. In terms of host endurance, would it not be more energy efficient to not have the bacteria process the food and utilized by the host directly?
In Figure 4, there is primary one direction from microbiome to the muscle, not too much illustration on the muscle to microbiome direction.
Section 7: Diet seems to affect host endurance directly and not through microbiome. I would recommend reducing the content in this section to focus on the main point of the review.
Section 9: Please change subtitle to “potential” mode of action on an Athlete's Endurance.
Content on section 8 and 10 should be rearranged. I would suggest having a separate section for probiotics only, and another for prebiotics, synbiotics, etc.
All the references are not readable due to lack of space in between words.
Author Response
Please see attached file
Author Response File: Author Response.pdf
Reviewer 2 Report
Comments and Suggestions for AuthorsPlease see attached
Comments for author File: Comments.pdf
Comments on the Quality of English LanguageEnglish language needs moderate editing.
Author Response
Please see attached file
Author Response File: Author Response.pdf
Round 2
Reviewer 1 Report
Comments and Suggestions for AuthorsThe manuscript is ready for acceptance.
Author Response
Thank you very much for your valuable comments and suggestions.
Reviewer 2 Report
Comments and Suggestions for AuthorsPlease see the attachment
Comments for author File: Comments.pdf
Comments on the Quality of English LanguageMinor English language changes required
Author Response
Please see attached file 16092024 Response to reviewer 2
Author Response File: Author Response.pdf