Si–Fe–C–N Coatings for Biomedical Applications: A Combinatorial Approach
Abstract
:1. Introduction
2. Materials and Methods
2.1. Coating Deposition
2.2. Material Characterization
2.2.1. Composition
2.2.2. Crystallinity, Surface, and Cross-Sectional Morphology
2.2.3. Hardness and Indentation Modulus
2.2.4. In Vitro Cell Study
2.2.5. Statistical Analysis
3. Results
3.1. Composition
3.2. Structure and Morphology
3.3. Mechanical Properties
3.4. Biocompatibility
4. Discussion
4.1. Composition and Thickness
4.2. Crystallinity, Surface and Cross-Section Morphology
4.3. Mechanical Properties
4.3.1. Hardness
4.3.2. Indentation Modulus
4.4. Cell Response
4.5. Limitations of the Study
4.6. Future Work
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Point | x [mm] | y [mm] | Si [at.%] | Fe [at.%] | C [at.%] | N [at.%] | O [at.%] | t [nm] | Ra [nm] | H [GPa] | M [GPa] | Cell Density [cell mm−2] |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 0 | 40 | 33.9 ± 0.5 | 10.2 ± 0.3 | 8.2 ± 0.1 | 47.2 ± 0.7 | 0.4 ± 0.1 | 633 | 1.9 ± 0.5 | 16.5 ± 1.2 | 212.1 ± 8.0 | 138 ± 42 |
2 | 40 | 40 | 27.6 ± 2.8 | 18.2 ± 3.4 | 10.0 ± 1.5 | 43.7 ± 0.9 | 0.5 ± 0.1 | 467 | 2.2 ± 0.3 | 13.7 ± 0.9 | 193.2 ± 6.9 | 63 ± 27 |
3 | 0 | 0 | 32.5 ± 0.4 | 9.6 ± 0.4 | 11.6 ± 0.3 | 46.0 ± 0.8 | 0.3 ± 0.2 | 630 | 1.7 ± 0.1 | 17.3 ± 0.7 | 210.6 ± 5.8 | 139 ± 58 |
4 | 40 | 0 | 26.0 ± 0.9 | 20.0 ± 0.3 | 13.9 ± 0.2 | 39.7 ± 0.7 | 0.6 ± 0.03 | 507 | 1.9 ± 0.1 | 14.7 ± 0.8 | 189.8 ± 6.9 | 81 ± 70 |
5 | 20 | 20 | 30.0 ± 0.1 | 13.8 ± 0.4 | 11.6 ± 0.2 | 44.2 ± 0.4 | 0.4 ± 0.1 | 576 | 1.9 ± 0.1 | 16.0 ± 1.1 | 204.4 ± 7.8 | 263 ± 167 |
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Skjöldebrand, C.; Hulsart-Billström, G.; Engqvist, H.; Persson, C. Si–Fe–C–N Coatings for Biomedical Applications: A Combinatorial Approach. Materials 2020, 13, 2074. https://doi.org/10.3390/ma13092074
Skjöldebrand C, Hulsart-Billström G, Engqvist H, Persson C. Si–Fe–C–N Coatings for Biomedical Applications: A Combinatorial Approach. Materials. 2020; 13(9):2074. https://doi.org/10.3390/ma13092074
Chicago/Turabian StyleSkjöldebrand, Charlotte, Gry Hulsart-Billström, Håkan Engqvist, and Cecilia Persson. 2020. "Si–Fe–C–N Coatings for Biomedical Applications: A Combinatorial Approach" Materials 13, no. 9: 2074. https://doi.org/10.3390/ma13092074