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Pediatric Reports
Volume 6
Issue 2
10.4081/pr.2014.5160
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Case Report

Two Cases of Esophageal Eosinophilia: Eosinophilic Esophagitis or Gastro-Esophageal Reflux Disease?

by
Ozlem Yilmaz
1,*,
Hacer Ilbilge Ertoy Karagol
1,
Erdem Topal
1,
Aysel Unlusoy Aksu
2,
Odul Egritas
2,
Ipek Isık Gonul
3 and
Arzu Bakirtas
1
1
Department of Pediatric Allergy and Asthma
2
Department of Pediatric Gastroenterology
3
Department of Pathology, Gazi University School of Medicine, Ankara, Turkey
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2014, 6(2), 5160; https://doi.org/10.4081/pr.2014.5160
Submission received: 6 November 2013 / Revised: 6 November 2013 / Accepted: 10 March 2014 / Published: 16 June 2014

Abstract

Eosinophilic esophagitis (EoE) and gastro-esophageal reflux disease are among the major causes of isolated esophageal eosinophilia. Isolated esophageal eosinophilia meeting criteria for EoE may respond to proton pump inhibitor (PPI) treatment. This entity is termed proton pumps inhibitor responsive esophageal eosinophilia (PPI-REE). Gastro-esophageal reflux is thought to comprise a subgroup of patients with PPI-REE. According to the latest guidelines, PPI responsiveness distinguishes people with PPI-REE from patients having EoE (non-responders). In this report, two unusual cases with findings belonging to both EoE and PPI-REE are discussed with known and unknown facts.
Keywords: children; eosinophils; esophagitis; proton pumps inhibitors children; eosinophils; esophagitis; proton pumps inhibitors

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MDPI and ACS Style

Yilmaz, O.; Ertoy Karagol, H.I.; Topal, E.; Unlusoy Aksu, A.; Egritas, O.; Gonul, I.I.; Bakirtas, A. Two Cases of Esophageal Eosinophilia: Eosinophilic Esophagitis or Gastro-Esophageal Reflux Disease? Pediatr. Rep. 2014, 6, 5160. https://doi.org/10.4081/pr.2014.5160

AMA Style

Yilmaz O, Ertoy Karagol HI, Topal E, Unlusoy Aksu A, Egritas O, Gonul II, Bakirtas A. Two Cases of Esophageal Eosinophilia: Eosinophilic Esophagitis or Gastro-Esophageal Reflux Disease? Pediatric Reports. 2014; 6(2):5160. https://doi.org/10.4081/pr.2014.5160

Chicago/Turabian Style

Yilmaz, Ozlem, Hacer Ilbilge Ertoy Karagol, Erdem Topal, Aysel Unlusoy Aksu, Odul Egritas, Ipek Isık Gonul, and Arzu Bakirtas. 2014. "Two Cases of Esophageal Eosinophilia: Eosinophilic Esophagitis or Gastro-Esophageal Reflux Disease?" Pediatric Reports 6, no. 2: 5160. https://doi.org/10.4081/pr.2014.5160

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