Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications
Abstract
:1. Introduction
2. Repeat Proteins as Scaffolds for Protein Engineering
2.1. Designed Ankyrin Repeat Proteins (DARPins)
2.2. Leucine Rich Repeats (LRRs)
2.3. Other Repeat Proteins
3. Block V RTX Domain of Adenylate Cyclase from Bordatella pertussis
4. Native RTX Domain Insertions for Introducing Calcium-Mediated Function
5. Exploring the Order of RTX Domain Repeat Sequence Lead to Useful Precipitation for Bioseparations
6. Engineered β-Roll Domains with Hydrophobic Faces for Self-Assembly and Protein Hydrogel Formation
7. Evolution of β-Roll Domains Exhibiting Calcium-Dependent Biomolecular Recognition
8. Summary and Conclusions
Acknowledgments
Conflicts of Interest
References
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Bulutoglu, B.; Banta, S. Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications. Toxins 2017, 9, 289. https://doi.org/10.3390/toxins9090289
Bulutoglu B, Banta S. Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications. Toxins. 2017; 9(9):289. https://doi.org/10.3390/toxins9090289
Chicago/Turabian StyleBulutoglu, Beyza, and Scott Banta. 2017. "Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications" Toxins 9, no. 9: 289. https://doi.org/10.3390/toxins9090289