Preparation of N-Halamine Gelatin Sponge and Its Application in the Treatment of Skin Infection
Abstract
:1. Introduction
2. Experimental Section
2.1. Materials
2.2. Measurements
2.3. Synthesis of Protein N-Halamines
2.4. Mechanical Properties Test
2.5. Characterization
2.6. Determination of GS-Cl Samples’ Chlorine Content
2.7. In Vitro Antibacterial Test
2.8. Biocompatibility Assay
2.9. In Vivo Wound Healing Study
3. Results and Discussion
3.1. The Influence of Chlorination Time and NaClO Concentrations on the Chlorine Contents
3.2. FTIR Analysis
3.3. XPS Analysis
3.4. SEM Analysis
3.5. Mechanical and Stability Studies
3.6. Antibacterial Activity
3.7. Biocompatibility
3.8. In Vivo Infectious Wound Healing Studies
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
References
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Zhu, J.; Xue, J.; Qin, H.; Wang, Y.; Wang, Y.; Cheng, Y.; Ma, Y.; Zhang, X.; Gong, C.; Zhao, G. Preparation of N-Halamine Gelatin Sponge and Its Application in the Treatment of Skin Infection. Polymers 2024, 16, 2579. https://doi.org/10.3390/polym16182579
Zhu J, Xue J, Qin H, Wang Y, Wang Y, Cheng Y, Ma Y, Zhang X, Gong C, Zhao G. Preparation of N-Halamine Gelatin Sponge and Its Application in the Treatment of Skin Infection. Polymers. 2024; 16(18):2579. https://doi.org/10.3390/polym16182579
Chicago/Turabian StyleZhu, Jiahao, Jiageng Xue, Huaiying Qin, Yiqing Wang, Yefan Wang, Yidan Cheng, Yingxia Ma, Xiaoyun Zhang, Chenliang Gong, and Guanghui Zhao. 2024. "Preparation of N-Halamine Gelatin Sponge and Its Application in the Treatment of Skin Infection" Polymers 16, no. 18: 2579. https://doi.org/10.3390/polym16182579