Autonomic Dysfunction and Cardiac Performance in Pregnant Women with Hypertensive Disorders: A Comparative Study Using Heart Rate Variability and Global Longitudinal Strain
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Heart Rate Variability Analysis and Cardiac Performance Evaluation
2.3. Statistical Analysis
3. Results
3.1. Study Group Description
3.2. HRV Analysis
3.3. Cardiac Performance Analysis
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameter | HDP | Control Group | p-Value (p) |
---|---|---|---|
MA (years) | 30.1 (4.2) | 28.2 (3.7) | 0.008 |
GA (weeks) | 27.3 (3.7) | 26.7 (3.9) | 0.357 |
SBP (mmHg) | 156.9 (9.6) | 122.4 (8.4) | <0.001 |
DBP (mmHg) | 100.9 (10.6) | 78.1 (5.5) | <0.001 |
HR (b/min) | 88.9 (10.3) | 86 (11.3) | 0.1148 |
Hb (g/L) | 12 (0.6) | 11.8 (0.7) | 0.157 |
BMI (kg/mp) | 29 (3.8) | 28.1 (4.3) | 0.188 |
Parameter | HDP Group | Control Group | p-Value (p) |
---|---|---|---|
SDNN (ms) | 113.85 (14.82) | 132.9 (9.61) | p < 0.001 |
RMSSD (ms) | 39.25 (5.10) | 59.75 (7.37) | |
pNN50 (%) | 12.88 (2.46) | 20.38 (2.46) | |
TP (ms2) | 2855 (321.36) | 3098.94 (188.91) | |
HF (ms2) | 394.17 (60.47) | 536.2 (68.94) | |
LF (ms2) | 956.7 (155.10) | 1086.08 (60.07) | |
LF/HF | 2.49 (0.59) | 2.05 (0.23) |
Parameter | GH Median (IQR) | PE Median (IQR) | SPE Median (IQR) | Chi-Squared | p-Value (p) |
---|---|---|---|---|---|
NN (ms) | 936 (83.5) | 931 (61.25) | 907 (62) | 1.05 | p = 0.589 |
SDNN (ms) | 117.7 (10.25) | 109.7 (6.82) | 117.2 (7.7) | 17.68 | p < 0.001 |
RMSSD (ms) | 41 (7.5) | 36 (8.5) | 42 (8) | 9.77 | p = 0.008 |
pNN50 (%) | 12.9 (3.65) | 11.9 (3.05) | 12 (4.9) | 3.69 | p = 0.158 |
TP (ms2) | 2905 (524) | 2728 (407) | 3111 (527) | 3.05 | p = 0.217 |
HF (ms2) | 403 (102.5) | 355 (94.5) | 352 (56) | 4.08 | p = 0.13 |
LF (ms2) | 931 (256) | 938 (264.5) | 1027 (191) | 1.13 | p = 0.566 |
LF/HF | 2.38 (0.9) | 2.71 (0.93) | 2.87 (0.65) | 4.56 | p = 0.102 |
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Bogdan, C.; Apostol, A.; Ivan, V.M.; Sandu, O.E.; Petre, I.; Petre, I.; Marc, L.-E.; Maralescu, F.-M.; Lighezan, D.F. Autonomic Dysfunction and Cardiac Performance in Pregnant Women with Hypertensive Disorders: A Comparative Study Using Heart Rate Variability and Global Longitudinal Strain. Life 2024, 14, 1039. https://doi.org/10.3390/life14081039
Bogdan C, Apostol A, Ivan VM, Sandu OE, Petre I, Petre I, Marc L-E, Maralescu F-M, Lighezan DF. Autonomic Dysfunction and Cardiac Performance in Pregnant Women with Hypertensive Disorders: A Comparative Study Using Heart Rate Variability and Global Longitudinal Strain. Life. 2024; 14(8):1039. https://doi.org/10.3390/life14081039
Chicago/Turabian StyleBogdan, Carina, Adrian Apostol, Viviana Mihaela Ivan, Oana Elena Sandu, Ion Petre, Izabella Petre, Luciana-Elena Marc, Felix-Mihai Maralescu, and Daniel Florin Lighezan. 2024. "Autonomic Dysfunction and Cardiac Performance in Pregnant Women with Hypertensive Disorders: A Comparative Study Using Heart Rate Variability and Global Longitudinal Strain" Life 14, no. 8: 1039. https://doi.org/10.3390/life14081039