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Review

Whole-Body SPECT/CT: Protocol Variation and Technical Consideration—A Narrative Review

by
Mansour M. Alqahtani
1,2
1
Department of Radiology and Medical Imaging, Faculty of Applied Medical Sciences, Najran University, Najran 61441, Saudi Arabia
2
Discipline of Medical Imaging Science, Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia
Diagnostics 2024, 14(16), 1827; https://doi.org/10.3390/diagnostics14161827 (registering DOI)
Submission received: 23 July 2024 / Revised: 13 August 2024 / Accepted: 16 August 2024 / Published: 21 August 2024
(This article belongs to the Topic AI in Medical Imaging and Image Processing)

Abstract

Introducing a hybrid imaging approach, such as single-photon emission computerized tomography with X-ray computed tomography (SPECT)/CT, improves diagnostic accuracy and patient management. The ongoing advancement of SPECT hardware and software has resulted in the clinical application of novel approaches. For example, whole-body SPECT/CT (WB-SPECT/CT) studies cover multiple consecutive bed positions, similar to positron emission tomography-computed tomography (PET/CT). WB-SPECT/CT proves to be a helpful tool for evaluating bone metastases (BM), reducing equivocal findings, and enhancing user confidence, displaying effective performance in contrast to planar bone scintigraphy (PBS). Consequently, it is increasingly utilized and might substitute PBS, which leads to new questions and issues concerning the acquisition protocol, patient imaging time, and workflow process. Therefore, this review highlights various aspects of WB-SPECT/CT acquisition protocols that need to be considered to help understand WB-SPECT/CT workflow processes and optimize imaging protocols.
Keywords: SPECT/CT; whole-body SPECT/CT; planar bone scintigraphy; bone metastases; acquisition protocol SPECT/CT; whole-body SPECT/CT; planar bone scintigraphy; bone metastases; acquisition protocol

Share and Cite

MDPI and ACS Style

Alqahtani, M.M. Whole-Body SPECT/CT: Protocol Variation and Technical Consideration—A Narrative Review. Diagnostics 2024, 14, 1827. https://doi.org/10.3390/diagnostics14161827

AMA Style

Alqahtani MM. Whole-Body SPECT/CT: Protocol Variation and Technical Consideration—A Narrative Review. Diagnostics. 2024; 14(16):1827. https://doi.org/10.3390/diagnostics14161827

Chicago/Turabian Style

Alqahtani, Mansour M. 2024. "Whole-Body SPECT/CT: Protocol Variation and Technical Consideration—A Narrative Review" Diagnostics 14, no. 16: 1827. https://doi.org/10.3390/diagnostics14161827

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