Ultrasound-Guided Cervical Selective Nerve Root Block versus Fluoroscopy-Guided Interlaminar Epidural Injection for Cervical Radicular Pain: A Randomized, Prospective, Controlled Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Design
2.2. Patients
2.3. Randomization and Blinding
2.4. Interventions
2.4.1. IL-CESI Group
2.4.2. CSNRB Group
2.5. Outcome Measurements
2.6. Sample Size Determination
2.7. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | IL-CESI (n = 30) | CSNRB (n = 30) | p Value |
---|---|---|---|
Age (years) | 54.23 ± 8.98 | 55.1 ± 10.03 | 0.555 |
Sex | |||
Male | 14 (46.7%) | 17 (56.7%) | 0.605 |
Female | 16 (53.3%) | 13 (43.3%) | |
BMI (kg/m2) | 24.02. ± 2.47 | 23.13 ± 2.52 | 0.914 |
Affected side | |||
Left | 17 (56.7%) | 15 (50%) | 0.796 |
Right | 13 (43.3%) | 15 (50%) | |
Pain duration (months) | 11.5 ± 5.83 | 10.13 ± 4.25 | 0.094 |
Target nerve root | |||
C5 | 3 (10%) | 2 (6.7%) | 0.716 |
C6 | 17 (56.7%) | 15 (50%) | |
C7 | 10 (33.3%) | 13 (43.3%) | |
Grade of nerve root compression | |||
Grade II | 19 (63.3%) | 15 (50%) | 0.550 |
Grade III | 10 (33.3%) | 13 (43.3%) | |
Grade IV | 1 (3.3%) | 2 (6.6%) |
IL-CESI | CSNRB | p | |
---|---|---|---|
NRS | |||
Baseline | 7 (6–8) | 6.5 (6–7.75) | 0.105 |
Month 1 | 1.5 (1–2) * | 1.5 (1–2.75) * | 0.776 |
Month 3 | 2 (2–3) * | 2 (2–2.75) * | 0.789 |
Month 6 | 3.5 (2–4) * | 3 (2–4) * | 0.927 |
Positive responders | |||
Month 1 | |||
n (%) (95% CI) | 25 (83.3%) (65.2–94.3) | 24 (80%) (61.4–92.2) | 0.753 |
Month 3 | |||
n (%) (95% CI) | 22 (73.3%) (54.1–87.7) | 23 (76.6%) (57.7–90) | 0.776 |
Month 6 | |||
n (%) (95% CI) | 17 (56.6%) (37.4–74.5) | 15 (50%) (31.3–68.7) | 0.617 |
NRS MCID | |||
Month 1 | |||
n (%) (95% CI) | 29 (96.7%) (82.7–99.9) | 28 (93.3%) (77.9–99.1) | 0.618 |
Month 3 | |||
n (%) (95% CI) | 27 (90%) (73.4–97.8) | 26 (86.7%) (69.2–96.2) | 0.711 |
Month 6 | |||
n (%) (95% CI) | 26 (86.7%) (69.2–96.2) | 25 (83.3%) (65.2–94.3) | 0.735 |
Variables | IL-CESI (n = 30) | CSNRB (n = 30) | p Value |
---|---|---|---|
NDI | |||
Baseline | 30.3 ± 12.11 | 28.23 ± 10.29 | 0.479 |
Month 1 | 13.7 ± 5.39 * | 13.63 ± 5.72 * | 0.963 |
Month 3 | 12.2 ± 7.45 * | 10.93 ± 5.26 * | 0.450 |
Month 6 | 12.9 ± 6.05 * | 11.5 ± 4.52 * | 0.315 |
PCS | |||
Baseline | 32.15 ± 20.23 | 29.84 ± 18.75 | 0.648 |
Month 1 | 39.34 ± 9.36 * | 37.25 ± 10.23 * | 0.412 |
Month 3 | 49.55 ± 8.96 * | 50.12 ± 9.72 * | 0.814 |
Month 6 | 47.83 ± 9.21 * | 46.93 ± 10.54 * | 0.726 |
MCS | |||
Baseline | 49.05 ± 17.93 | 47.26 ± 16.95 | 0.692 |
Month 1 | 52.62 ± 10.91 * | 49.33 ± 12.25 * | 0.276 |
Month 3 | 58.76 ± 11.34 * | 54.35 ± 13.21 * | 0.170 |
Month 6 | 56.42 ± 11.21 * | 52.97 ± 12.34 * | 0.261 |
QAQ | |||
Baseline | 4.93 ± 2.03 | 4.46 ± 1.87 | 0.661 |
Month 6 | 1.63 ± 0.66 * | 1.46 ± 0.68 * | 0.329 |
Patient Satisfaction | |||
Month 6 | 4 (4–5) | 4 (3.25–5) | 0.374 |
Procedure Time | |||
Seconds | 208.76 ± 96.2 | 352.42 ± 103.61 | <0.001 |
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Kose, H.C.; Guven Kose, S.; Celikel, F.; Tulgar, S.; Akkaya, O.T. Ultrasound-Guided Cervical Selective Nerve Root Block versus Fluoroscopy-Guided Interlaminar Epidural Injection for Cervical Radicular Pain: A Randomized, Prospective, Controlled Study. J. Pers. Med. 2024, 14, 721. https://doi.org/10.3390/jpm14070721
Kose HC, Guven Kose S, Celikel F, Tulgar S, Akkaya OT. Ultrasound-Guided Cervical Selective Nerve Root Block versus Fluoroscopy-Guided Interlaminar Epidural Injection for Cervical Radicular Pain: A Randomized, Prospective, Controlled Study. Journal of Personalized Medicine. 2024; 14(7):721. https://doi.org/10.3390/jpm14070721
Chicago/Turabian StyleKose, Halil Cihan, Selin Guven Kose, Feyza Celikel, Serkan Tulgar, and Omer Taylan Akkaya. 2024. "Ultrasound-Guided Cervical Selective Nerve Root Block versus Fluoroscopy-Guided Interlaminar Epidural Injection for Cervical Radicular Pain: A Randomized, Prospective, Controlled Study" Journal of Personalized Medicine 14, no. 7: 721. https://doi.org/10.3390/jpm14070721