Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp.
Abstract
:1. Actinobacteria and Their Primary Metabolism as Basis for Secondary Metabolism Precursor Supply
1.1. Carbon Metabolism as a Source of Precursors
1.2. Primary Metabolism in Actinobacteria: Nitrogen Metabolism
1.2.1. Biochemistry of Nitrogen Metabolism
1.2.2. Regulation of Nitrogen Metabolism in Actinobacteria
1.3. Primary Metabolism in Actinobacteria: Phosphate Metabolism
1.3.1. Biochemistry of Phosphate Metabolism
1.3.2. Regulation of Phosphate Metabolism
1.4. Primary Metabolism in Actinobacteria: Sulfur Metabolism
2. Specialized Metabolic Pathways for Supply of Alternative Precursors for Secondary Metabolism
2.1. Alternative Metabolism in Actinobacteria—Polyamine Metabolism
2.2. Alternative Metabolism in Actinobacteria—Ethanolamine Metabolism
2.3. Exoenzymes and Proteases
3. Utilization of Precursor Compounds from Primary Metabolism in Secondary Metabolism
3.1. Secondary Metabolism in Actinobacteria
3.2. Supply of Key Precursors Carbon, Nitrogen, Phosphate and Sulfur for Secondary Metabolism
3.2.1. Supply of Carbon for Secondary Metabolism
3.2.2. Supply of Nitrogen for Secondary Metabolism
3.2.3. Supply of Phosphate for Secondary Metabolism
3.2.4. Supply of Sulfur for Secondary Metabolism
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Krysenko, S.; Wohlleben, W. Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp. Microorganisms 2024, 12, 1571. https://doi.org/10.3390/microorganisms12081571
Krysenko S, Wohlleben W. Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp. Microorganisms. 2024; 12(8):1571. https://doi.org/10.3390/microorganisms12081571
Chicago/Turabian StyleKrysenko, Sergii, and Wolfgang Wohlleben. 2024. "Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp." Microorganisms 12, no. 8: 1571. https://doi.org/10.3390/microorganisms12081571