Breast-Specific Gamma Imaging with [99mTc]Tc-Sestamibi: An In Vivo Analysis for Early Identification of Breast Cancer Lesions Expressing Bone Biomarkers
Abstract
:1. Introduction
2. Methods
2.1. [99mTc]Tc-Sestamibi–High Resolution SPECT
2.2. Histology
2.3. Immunohistochemistry
2.4. EDX Microanalysis
2.5. Statistical Analysis
3. Results
3.1. 99mTc-Sestamibi–High Resolution SPECT Analysis
3.2. Histology
3.3. Sestamibi Uptake vs. BOLCs
3.4. Sestamibi Uptake vs. BOLCs’ Main Markers
3.5. EDX Microanalysis
3.6. Sestamibi Uptake vs. Microcalcifications
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Urbano, N.; Scimeca, M.; Di Russo, C.; Bonanno, E.; Schillaci, O. Breast-Specific Gamma Imaging with [99mTc]Tc-Sestamibi: An In Vivo Analysis for Early Identification of Breast Cancer Lesions Expressing Bone Biomarkers. J. Clin. Med. 2020, 9, 747. https://doi.org/10.3390/jcm9030747
Urbano N, Scimeca M, Di Russo C, Bonanno E, Schillaci O. Breast-Specific Gamma Imaging with [99mTc]Tc-Sestamibi: An In Vivo Analysis for Early Identification of Breast Cancer Lesions Expressing Bone Biomarkers. Journal of Clinical Medicine. 2020; 9(3):747. https://doi.org/10.3390/jcm9030747
Chicago/Turabian StyleUrbano, Nicoletta, Manuel Scimeca, Carmela Di Russo, Elena Bonanno, and Orazio Schillaci. 2020. "Breast-Specific Gamma Imaging with [99mTc]Tc-Sestamibi: An In Vivo Analysis for Early Identification of Breast Cancer Lesions Expressing Bone Biomarkers" Journal of Clinical Medicine 9, no. 3: 747. https://doi.org/10.3390/jcm9030747