Evaluating Pressure Variability and Influencing Factors during High-Flow Nasal Cannula Therapy in Premature Infants
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients
2.2. Pressure Measurements during HHHFNC Therapy
2.3. Covariates and Outcome Measures
2.4. Statistical Analysis
3. Results
3.1. Participants
3.2. Analysis of Factors That Affect Generated Pressure of HHHFNCs
3.3. Adverse Events
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Mean | Median | |
---|---|---|
Birth gestation (weeks) | 28.33 ± 2.61 | 28.4 |
Birth weight (g) | 1102 ± 327.53 | 1153 |
1 min Apgar score | 3.89 ± 1.76 | 4 |
5 min Apgar score | 6 ± 2.24 | 6 |
Respiratory support with HHHFNCs | ||
PMA (weeks) | 46.67 ± 26.83 | 30 |
PMA (days) | 244.44 ± 19.74 | 238 |
Current weight (g) | 2083 ± 11 | 1917 |
Flow (L/min) | 3.83 ± 0.56 | 4 |
Pressure (cmH2O) | 4.89 ± 0.81 | 5 |
Duration (days) | 20.89 ± 4.73 | 21 |
Participant | Mean | Median | Std. Deviation | Coefficient of Variation | |
---|---|---|---|---|---|
Mean Centered | Median Centered | ||||
1 | 4.995 | 5.000 | 0.338 | 6.8% | 6.8% |
2 | 2.450 | 2.450 | 0.316 | 13.2% | 13.1% |
3 | 1.333 | 1.333 | 0.168 | 11.5% | 16.1% |
4 | 1.250 | 1.250 | 0.169 | 13.5% | 13.5% |
5 | 0.667 | 0.667 | 0.087 | 12.2% | 14.8% |
6 | 0.857 | 0.857 | 0.081 | 9.3% | 9.7% |
7 | 0.638 | 0.625 | 0.033 | 5.2% | 5.7% |
8 | 0.667 | 0.667 | 0.080 | 12.6% | 12.5% |
9 | 0.518 | 0.518 | 0.060 | 11.9% | 12.0% |
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Ho, F.-C.; Lin, C.-Y.; Chang, A.-S.; Yeh, C.-Y.; Chen, H.-L. Evaluating Pressure Variability and Influencing Factors during High-Flow Nasal Cannula Therapy in Premature Infants. Children 2024, 11, 995. https://doi.org/10.3390/children11080995
Ho F-C, Lin C-Y, Chang A-S, Yeh C-Y, Chen H-L. Evaluating Pressure Variability and Influencing Factors during High-Flow Nasal Cannula Therapy in Premature Infants. Children. 2024; 11(8):995. https://doi.org/10.3390/children11080995
Chicago/Turabian StyleHo, Fong-Cheng, Chia-Ying Lin, Ane-Shu Chang, Ching-Yi Yeh, and Hsiu-Lin Chen. 2024. "Evaluating Pressure Variability and Influencing Factors during High-Flow Nasal Cannula Therapy in Premature Infants" Children 11, no. 8: 995. https://doi.org/10.3390/children11080995