Chiral Dualism as a Unifying Principle in Molecular Biophysics
Abstract
:1. Introduction
2. Chirality of Macromolecules
2.1. Proteins
2.1.1. Primary and Secondary Structure
2.1.2. Superhelices
2.1.3. Cytoskeleton
2.2. DNA
3. Chiral Hierarchy Establishment
4. Chirality of Drugs
4.1. Drugs with a Bioactive “Left-Handed” S-Enantiomer
4.2. Drugs with A Bioactive “Right-Handed” R-Enantiomer
4.3. Drugs with Two Bioactive Enantiomers
5. Discussion
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Malyshko, E.V.; Semenova, E.V.; Bagrova, O.E.; Murtazina, A.R.; Tverdislov, V.A. Chiral Dualism as a Unifying Principle in Molecular Biophysics. Biophysica 2021, 1, 22-37. https://doi.org/10.3390/biophysica1010003
Malyshko EV, Semenova EV, Bagrova OE, Murtazina AR, Tverdislov VA. Chiral Dualism as a Unifying Principle in Molecular Biophysics. Biophysica. 2021; 1(1):22-37. https://doi.org/10.3390/biophysica1010003
Chicago/Turabian StyleMalyshko, Ekaterina V., Ekaterina V. Semenova, Olga E. Bagrova, Alina R. Murtazina, and Vsevolod A. Tverdislov. 2021. "Chiral Dualism as a Unifying Principle in Molecular Biophysics" Biophysica 1, no. 1: 22-37. https://doi.org/10.3390/biophysica1010003