As all of the articles published in Brain Sciences (ISSN: 2076-3425) are of an open access format, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2021 and 2022 listed below:

1. “Renal Involvement in Hereditary Transthyretin Amyloidosis: An Italian Single-Centre Experience”
by Pietro Manuel Ferraro, Viola D’Ambrosio, Andrea Di Paolantonio, Valeria Guglielmino, Paolo Calabresi, Mario Sabatelli and Marco Luigetti
Brain Sci. 2021, 11(8), 980; https://doi.org/10.3390/brainsci11080980
Available online: https://www.mdpi.com/2076-3425/11/8/980

2. “Blood Serum Cytokines in Patients with Subacute Spinal Cord Injury: A Pilot Study to Search for Biomarkers of Injury Severity”
by Sergei Ogurcov, Iliya Shulman, Ekaterina Garanina, Davran Sabirov, Irina Baichurina, Maxim Kuznetcov, Galina Masgutova, Alexander Kostennikov, Albert Rizvanov, Victoria James et al.
Brain Sci. 2021, 11(3), 322; https://doi.org/10.3390/brainsci11030322
Available online: https://www.mdpi.com/2076-3425/11/3/322

3. “Transcutaneous Spinal Cord Stimulation Enhances Walking Performance and Reduces Spasticity in Individuals with Multiple Sclerosis”
by Ursula S. Hofstoetter, Brigitta Freundl, Peter Lackner and Heinrich Binder
Brain Sci. 2021, 11(4), 472; https://doi.org/10.3390/brainsci11040472
Available online: https://www.mdpi.com/2076-3425/11/4/472

4. “Challenges in Treating Charcot-Marie-Tooth Disease and Related Neuropathies: Current Management and Future Perspectives”
by Chiara Pisciotta, Paola Saveri and Davide Pareyson
Brain Sci. 2021, 11(11), 1447; https://doi.org/10.3390/brainsci11111447
Available online: https://www.mdpi.com/2076-3425/11/11/1447

5. “Using Machine Learning Algorithms for Identifying Gait Parameters Suitable to Evaluate Subtle Changes in Gait in People with Multiple Sclerosis”
by Katrin Trentzsch, Paula Schumann, Grzegorz Śliwiński, Paul Bartscht, Rocco Haase, Dirk Schriefer, Andreas Zink, Andreas Heinke, Thurid Jochim, Hagen Malberg et al.
Brain Sci. 2021, 11(8), 1049; https://doi.org/10.3390/brainsci11081049
Available online: https://www.mdpi.com/2076-3425/11/8/1049

6. “Use of Drugs for ATTRv Amyloidosis in the Real World: How Therapy Is Changing Survival in a Non-Endemic Area”
by Massimo Russo, Luca Gentile, Vincenzo Di Stefano, Gianluca Di Bella, Fabio Minutoli, Antonio Toscano, Filippo Brighina, Giuseppe Vita and Anna Mazzeo
Brain Sci. 2021, 11(5), 545; https://doi.org/10.3390/brainsci11050545
Available online: https://www.mdpi.com/2076-3425/11/5/545

7. “Intensive Care Unit-Acquired Weakness and Positioning-Related Peripheral Nerve Injuries in COVID-19: A Case Series of Three Patients and the Latest Literature Review”
by Keiichi Hokkoku, Carmen Erra, Cristina Cuccagna, Daniele Coraci, Dario Mattia Gatto, Davide Glorioso and Luca Padua
Brain Sci. 2021, 11(9), 1177; https://doi.org/10.3390/brainsci11091177
Available online: https://www.mdpi.com/2076-3425/11/9/1177

8. “Improving Digital Patient Care: Lessons Learned from Patient-Reported and Expert-Reported Experience Measures for the Clinical Practice of Multidimensional Walking Assessment”
by Maria Scholz, Rocco Haase, Katrin Trentzsch, Heidi Stölzer-Hutsch and Tjalf Ziemssen
Brain Sci. 2021, 11(6), 786; https://doi.org/10.3390/brainsci11060786
Available online: https://www.mdpi.com/2076-3425/11/6/786

9. “Restless Legs Syndrome: Known Knowns and Known Unknowns”
by Elena Antelmi, Lorenzo Rocchi, Anna Latorre, Daniele Belvisi, Francesca Magrinelli, Kailash P. Bhatia and Michele Tinazzi
Brain Sci. 2022, 12(1), 118; https://doi.org/10.3390/brainsci12010118
Available online: https://www.mdpi.com/2076-3425/12/1/118

10. “Sex Differences in Parkinson’s Disease: From Bench to Bedside”
by Maria Claudia Russillo, Valentina Andreozzi, Roberto Erro, Marina Picillo, Marianna Amboni, Sofia Cuoco, Paolo Barone and Maria Teresa Pellecchia
Brain Sci. 2022, 12(7), 917; https://doi.org/10.3390/brainsci12070917
Available online: https://www.mdpi.com/2076-3425/12/7/917

11. “Vitamin D Status and Parkinson’s Disease”
by Michela Barichella, Federica Garrì, Serena Caronni, Carlotta Bolliri, Luciano Zocchi, Maria Carmela Macchione, Valentina Ferri, Daniela Calandrella and Gianni Pezzoli
Brain Sci. 2022, 12(6), 790; https://doi.org/10.3390/brainsci12060790
Available online: https://www.mdpi.com/2076-3425/12/6/790

12. “Tics and Emotions”
by Gerry Leisman and Dana Sheldon
Brain Sci. 2022, 12(2), 242; https://doi.org/10.3390/brainsci12020242
Available online: https://www.mdpi.com/2076-3425/12/2/242

13. “Epidemiology of Progressive Supranuclear Palsy: Real World Data from the Second Largest Health Plan in Israel”
by Yael Barer, Gabriel Chodick, Raanan Cohen, Meital Grabarnik-John, Xiaolan Ye, Jorge Zamudio and Tanya Gurevich
Brain Sci. 2022, 12(9), 1126; https://doi.org/10.3390/brainsci12091126
Available online: https://www.mdpi.com/2076-3425/12/9/1126

14. “Molecular Imaging in Parkinsonian Disorders—What’s New and Hot?”
by Stéphane Prange, Hendrik Theis, Magdalena Banwinkler and Thilo van Eimeren
Brain Sci. 2022, 12(9), 1146; https://doi.org/10.3390/brainsci12091146
Available online: https://www.mdpi.com/2076-3425/12/9/1146

15. “Pimavanserin and Parkinson’s Disease Psychosis: A Narrative Review”
by Jamir Pitton Rissardo, Ícaro Durante, Idan Sharon and Ana Letícia Fornari Caprara
Brain Sci. 2022, 12(10), 1286; https://doi.org/10.3390/brainsci12101286
Available online: https://www.mdpi.com/2076-3425/12/10/1286

16. “EEG Correlates of Active Stopping and Preparation for Stopping in Chronic Tic Disorder”
by Alonso Zea Vera, Ernest V. Pedapati, Travis R. Larsh, Kevin Kohmescher, Makoto Miyakoshi, David A. Huddleston, Hannah S. Jackson, Donald L. Gilbert, Paul S. Horn and Steve W. Wu
Brain Sci. 2022, 12(2), 151; https://doi.org/10.3390/brainsci12020151
Available online: https://www.mdpi.com/2076-3425/12/2/151

17. “A Novel SETX Mutation in a Taiwanese Patient with Autosomal Recessive Cerebellar Ataxia Detected by Targeted Next-Generation Sequencing, and a Literature Review”
by Ping-I Chiang, Ting-Wei Liao and Chiung-Mei Chen
Brain Sci. 2022, 12(2), 173; https://doi.org/10.3390/brainsci12020173
Available online: https://www.mdpi.com/2076-3425/12/2/173

18. “Rasagiline Withdrawal Syndrome in Parkinson’s Disease”
by Paolo Solla, Tommaso Ercoli, Carla Masala, Gianni Orofino, Laura Fadda, Davide Giacomo Corda, Ignazio Roberto Zarbo, Mario Meloni, Elia Sechi, Caterina Francesca Bagella et al.
Brain Sci. 2022, 12(2), 219; https://doi.org/10.3390/brainsci12020219
Available online: https://www.mdpi.com/2076-3425/12/2/219

19. “Exercise Effects on Motor Skill Consolidation and Intermuscular Coherence Depend on Practice Schedule”
by Ali Khan, Jyotpal Singh, J. Patrick Neary and Cameron S. Mang
Brain Sci. 2022, 12(4), 436; https://doi.org/10.3390/brainsci12040436
Available online: https://www.mdpi.com/2076-3425/12/4/436

20. “Association between General Movements Assessment and Later Motor Delay (excluding Cerebral Palsy) in Low-Birth-Weight Infants”
by Hirotaka Gima and Tomohiko Nakamura
Brain Sci. 2022, 12(6), 686; https://doi.org/10.3390/brainsci12060686
Available online: https://www.mdpi.com/2076-3425/12/6/686