The “Neurodegenerative Diseases” Section of Brain Sciences (ISSN: 2076-3425) aims to publish articles on amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, prion diseases, etc.

As all the articles published in our journal are of an open access format, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers from 2021 and 2022, listed below:

1. “Frequency and Determinants of Olfactory Hallucinations in Parkinson’s Disease Patients”
by Paolo Solla, Carla Masala, Ilenia Pinna, Tommaso Ercoli, Francesco Loy, Gianni Orofino, Laura Fadda and Giovanni Defazio
Brain Sci. 2021, 11(7), 841; https://doi.org/10.3390/brainsci11070841
Available online: https://www.mdpi.com/2076-3425/11/7/841

2. “Improved Transfer-Learning-Based Facial Recognition Framework to Detect Autistic Children at an Early Stage”
by Tania Akter, Mohammad Hanif Ali, Md. Imran Khan, Md. Shahriare Satu, Md. Jamal Uddin, Salem A. Alyami, Sarwar Aliand, AKM Azad and Mohammad Ali Moni
Brain Sci. 2021, 11(6), 734; https://doi.org/10.3390/brainsci11060734
Available online: https://www.mdpi.com/2076-3425/11/6/734

3. “Gender Differences in Misdiagnosis and Delayed Diagnosis among Adults with Autism Spectrum Disorder with No Language or Intellectual Disability”
by Camilla Gesi, Giovanni Migliarese, Sara Torriero, Martina Capellazzi, Anna Caterina Omboni, Giancarlo Cerveri and Claudio Mencacci
Brain Sci. 2021, 11(7), 912; https://doi.org/10.3390/brainsci11070912
Available online: https://www.mdpi.com/2076-3425/11/7/912

4. “Investigating the Relationship between Autistic Traits, Ruminative Thinking, and Suicidality in a Clinical Sample of Subjects with Bipolar Disorder and Borderline Personality Disorder”
by Liliana Dell’Osso, Ivan Mirko Cremone, Giulia Amatori, Andrea Cappelli, Alessandro Cuomo, Stefano Barlati, Gabriele Massimetti, Antonio Vita, Andrea Fagiolini, Claudia Carmassi et al.
Brain Sci. 2021, 11(5), 621; https://doi.org/10.3390/brainsci11050621
Available online: https://www.mdpi.com/2076-3425/11/5/621

5. “Autistic Traits and Attention-Deficit Hyperactivity Disorder Symptoms Predict the Severity of Internet Gaming Disorder in an Italian Adult Population”
by Carmen Concerto, Alessandro Rodolico, Chiara Avanzato, Laura Fusar-Poli, Maria Salvina Signorelli, Fortunato Battaglia and Eugenio Aguglia
Brain Sci. 2021, 11(6), 774; https://doi.org/10.3390/brainsci11060774
Available online: https://www.mdpi.com/2076-3425/11/6/774

6. “Gastroparesis in Parkinson Disease: Pathophysiology, and Clinical Management”
by Heithem Soliman, Benoit Coffin and Guillaume Gourcerol
Brain Sci. 2021, 11(7), 831; https://doi.org/10.3390/brainsci11070831
Available online: https://www.mdpi.com/2076-3425/11/7/831

7. “Psychometric Evaluation of Social Cognition and Behavior Measures in Children and Adolescents with Down Syndrome”
by Emily K. Schworer, Emily K. Hoffman and Anna J. Esbensen
Brain Sci. 2021, 11(7), 836; https://doi.org/10.3390/brainsci11070836
Available online: https://www.mdpi.com/2076-3425/11/7/836

8. “Pomegranate Juice Ameliorates Dopamine Release and Behavioral Deficits in a Rat Model of Parkinson’s Disease”
by Małgorzata Kujawska, Michael Jourdes, Łukasz Witucki, Marta Karaźniewicz-Łada, Michał Szulc, Agata Górska, Przemysław Ł. Mikołajczak, Pierre-Louis Teissedre and Jadwiga Jodynis-Liebert
Brain Sci. 2021, 11(9), 1127; https://doi.org/10.3390/brainsci11091127
Available online: https://www.mdpi.com/2076-3425/11/9/1127

9. “Neuropsychiatric Symptoms in Parkinson’s Disease Patients Are Associated with Reduced Health-Related Quality of Life and Increased Caregiver Burden”
by Hannah von Eichel, Johanne Heine, Florian Wegner, Sophia Rogozinski, Stephanie Stiel, Adrian Groh, Lea Krey, Günter U. Höglinger and Martin Klietz
Brain Sci. 2022, 12(1), 89; https://doi.org/10.3390/brainsci12010089
Available online: https://www.mdpi.com/2076-3425/12/1/89

10. “Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease”
by Kristina Rosqvist, Anette Schrag, Per Odin and the CLaSP Consortium
Brain Sci. 2022, 12(1), 111; https://doi.org/10.3390/brainsci12010111
Available online: https://www.mdpi.com/2076-3425/12/1/111

11. “A Peek into Pandora’s Box: COVID-19 and Neurodegeneration”
by Abhishek Chandra and Ashu Johri
Brain Sci. 2022, 12(2), 190; https://doi.org/10.3390/brainsci12020190
Available online: https://www.mdpi.com/2076-3425/12/2/190

12. “Opicapone Improves Global Non-Motor Symptoms Burden in Parkinson’s Disease: An Open-Label Prospective Study”
by Diego Santos García, Gustavo Fernández Pajarín, Juan Manuel Oropesa-Ruiz, Francisco Escamilla Sevilla, Raúl Rashid Abdul Rahim López and José Guillermo Muñoz Enríquez
Brain Sci. 2022, 12(3), 383; https://doi.org/10.3390/brainsci12030383
Available online: https://www.mdpi.com/2076-3425/12/3/383

13. “Understanding the Burdens Associated with Huntington’s Disease in Manifest Patients and Care Partners–Comparing to Parkinson’s Disease and the General Population”
by Alex Exuzides, Joana E. Matos, Anisha M. Patel, Ashley A. Martin, Bryan Ricker and Danny Bega
Brain Sci. 2022, 12(2), 161; https://doi.org/10.3390/brainsci12020161
Available online: https://www.mdpi.com/2076-3425/12/2/161

14. “Olfactory Impairment in Parkinson’s Disease Patients with Tremor Dominant Subtype Compared to Those with Akinetic Rigid Dominant Subtype: A Pilot Study”
by Paolo Solla, Carla Masala, Tommaso Ercoli, Gianni Orofino, Francesco Loy, Ilenia Pinna, Laura Fadda and Giovanni Defazio.
Brain Sci. 2022, 12(2), 196; https://doi.org/10.3390/brainsci12020196
Available online: https://www.mdpi.com/2076-3425/12/2/196

15. “Caregiver Burden in Partners of Parkinsonian Patients with Deep Brain Stimulation”
by Eileen Gülke and Monika Pötter-Nerger
Brain Sci. 2022, 12(2), 238; https://doi.org/10.3390/brainsci12020238
Available online: https://www.mdpi.com/2076-3425/12/2/238

16. “Cognitive and Affective Theory of Mind across Adulthood”
by Simona Raimo, Maria Cropano, María Dolores Roldán-Tapia, Lidia Ammendola, Daniela Malangone and Gabriella Santangelo
Brain Sci. 2022, 12(7), 899; https://doi.org/10.3390/brainsci12070899
Available online: https://www.mdpi.com/2076-3425/12/7/899

17. “Resilience in People with Lewy Body Disorders and Their Care Partners: Association with Mental Health, Relationship Satisfaction, and Care Burden”
by Sabina Vatter and Iracema Leroi
Brain Sci. 2022, 12(2), 148; https://doi.org/10.3390/brainsci12020148
Available online: https://www.mdpi.com/2076-3425/12/2/148

18. “Sexual Dysfunctions in Parkinson’s Disease and Their Influence on Partnership—Data of the PRISM Study”
by Thomas Kinateder, Daniela Marinho, Doreen Gruber, Laura Hatzler, Georg Ebersbach and Florin Gandor
Brain Sci. 2022, 12(2), 159; https://doi.org/10.3390/brainsci12020159
Available online: https://www.mdpi.com/2076-3425/12/2/159

19. “Gender Differences in Demographic and Pharmacological Factors in Patients Diagnosed with Late-Onset of Alzheimer’s Disease”
by Melissa J. Bailey-Taylor, Nicolas Poupore, Laurie Theriot Roley, Richard L. Goodwin, Brooks Mcphail and Thomas I. Nathaniel
Brain Sci. 2022, 12(2), 160; https://doi.org/10.3390/brainsci12020160
Available online: https://www.mdpi.com/2076-3425/12/2/160

20. “Characterization of Ex Vivo and In Vitro Wnt Transcriptome Induced by Spinal Cord Injury in Rat Microglial Cells”
by Carlos González-Fernández, Pau González, Francisco González-Pérez and Francisco Javier Rodríguez
Brain Sci. 2022, 12(6), 708; https://doi.org/10.3390/brainsci12060708
Available online: https://www.mdpi.com/2076-3425/12/6/708