Reprint

Nitro Compounds and Their Derivatives in Organic Synthesis

Edited by
September 2020
120 pages
  • ISBN978-3-03943-148-9 (Hardback)
  • ISBN978-3-03943-149-6 (PDF)

This book is a reprint of the Special Issue Nitro Compounds and Their Derivatives in Organic Synthesis that was published in

Chemistry & Materials Science
Medicine & Pharmacology
Summary
Nitro chemistry plays an important role in organic synthesis to construct new frameworks. This is due to the diverse properties of the nitro group. The strong electron-withdrawing ability of the nitro group reduces the electron density of the scaffold, facilitating reactions with nucleophiles or electron transfer. In addition, the -hydrogen of the nitro group is highly acidic, giving a stable anion, which facilitates reactions with both electrophilic and nucleophilic reagents. In addition, the nitro group also serves as a good leaving group, which facilitates transformation to a wide variety of functional groups. Despite the substantial contributions of many researchers, nitro chemistry is still an exciting and challenging research area. This book brings together recent original research and review articles contributed by an international team of leading experts and pioneers in organic synthesis using nitro groups. It is sure to provide useful information and promising insights for researchers.
Format
  • Hardback
License and Copyright
© 2020 by the authors; CC BY-NC-ND license
Keywords
nitro; pyridone; 1-methyl-2-quinolone; cycloaddition; direct functionalization; perylenediimide; nitro group; organic materials; Phenacylation of beta-nitropyridin-2-ones; 8-nitro-5-RO-indolizines; oxazole-pyrrole ring transformation; conjugate addition; dihydrofuran; 1,3-dicarbonyl compound; enolate; isoxazoline N-oxide; nitro group; nitroketone; nitronate; nucleophilic substitution; nitro group; nitropyridines; isoxazolo[4,3-b]pyridines; 1,4-dihydropyridines; nucleophilic addition; Diels-Alder reaction; dearomatization; hexapyrrolohexaazacoronene; nitration; SNAr substitution; ICT character; aromaticity; C–H functionalization; total synthesis; pyrrolidines; anchimeric assistance; epimerization; PDE4 inhibitors; nitro group; conjugate addition; 1,3-Dipole; electron-withdrawing ability; electrophilicity; nitration; nitronate; nucleophilicity