Reprint

Micro/Nanofluidic Devices for Single Cell Analysis, Volume II

Edited by
February 2022
160 pages
  • ISBN978-3-0365-2919-6 (Hardback)
  • ISBN978-3-0365-2918-9 (PDF)

This book is a reprint of the Special Issue Micro/Nanofluidic Devices for Single Cell Analysis, Volume II that was published in

Chemistry & Materials Science
Engineering
Physical Sciences
Summary

This Special Issue book entitled “Micro/nanofluidic devices for Single Cell Analysis, Volume II” covers different aspects of single-cell analysis. This book emphasizes in detail single-cell separation, manipulation, and analysis and diagnosis. It also covers single-nucleus electrical characterization, hydrodynamic stretching, microsieve filtration for genetic, phenotypic analysis which links to cellular deformability and the clinical application of an integrated microfluidic device for the isolation of circulating tumor cells and analysis. Moreover, this book describes single-cell mechanophenotyping to evaluate the behavior of U87 Glioma cells, with the heterogeneity being quantified according to the deformation of the U937 monocytes and U937-differentiated macrophages. Finally, this book also demonstrated the real-time monitoring and detection of single-cell level cytokine secretion using LSPR technology.

Format
  • Hardback
License and Copyright
© 2022 by the authors; CC BY-NC-ND license
Keywords
microfluidics; single-nucleus analysis; constriction channel; electrical properties; nuclear envelope; localized surface plasmon resonance (LSPR) technology; Interleukin 6 (IL-6) detection; single cell trapping; single cell level immunoassay; micronozzle-array; parallel cell manipulation; bidirectional electrokinetic pump; DC biased AC electrokinetic flow; microfluidics; single cell level; diagnostics; biomedical engineering; parasites; cancer; infectious diseases; point-of-care; cancer metastasis; deformability; epithelial to mesenchymal transition; TP53 genes; chemotherapy drug; microfluidic hydrodynamic stretching; microsieve; dielectrophoresis; deformation; mobility; heterogeneity; macrophage; monocyte; glioblastoma; mechanophenotyping; deformation; migration; Label-free; single-cell; imaging flow cytometer; precise velocity measurement; single-shot image-based velocity measurement; particle shape reconstruction; multi-view imaging; exposure time difference; CTC-isolation; microfluidics; single-cell analysis; high-throughput sequencing; lung cancer; n/a