Hypertrophic Cardiomyopathy—Current Challenges and Future Perspectives

Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by left ventricular hypertrophy, which cannot be entirely attributed to loading conditions such as valve or congenital heart disease, or hypertension. This condition is relatively common, with a prevalence of 1:250–500 individuals, and is linked to increased rates of mortality and morbidity. In recent years, there has been a growing body of knowledge concerning the genetic underpinnings, natural history, risk assessment, and management of HCM.

In this Special Issue, experts in the field delve into these topics through comprehensive reviews and original articles that explores the molecular basis, the role of genetic testing, risk stratification for sudden cardiac death, atrial fibrillation, and management of HCM.