Reprint

Current State of the Field of Cell-Penetrating Peptides as an Honorific Issue for Professor Ülo Langel

Edited by
June 2024
234 pages
  • ISBN978-3-7258-1258-5 (Hardback)
  • ISBN978-3-7258-1257-8 (PDF)

This book is a reprint of the Special Issue Current State of the Field of Cell-Penetrating Peptides as an Honorific Issue for Professor Ülo Langel that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

This Special Issue entitled, initiated by the editorial team of Pharmaceutics, pays homage to Professor Ülo Langel for his remarkable scientific contribution to the field of cell-penetrating peptides (CPPs). Prof. Langel graduated from Tartu University, Tartu, Estonia, as a bioorganic chemist in 1974. He has obtained two PhD degrees: in 1980 from Tartu University, Tartu, Estonia (bioorganic chemistry), and in 1993 from Tartu University/Stockholm University (biochemistry/neurochemistry). Prof. Langel is a Professor at the Department of Biochemistry and Biophysics, Stockholm University, and at the Institute of Technology, Tartu University. Furthermore, he is an Associate Professor at The Scripps Research Institute, La Jolla, CA, USA and Honorary Professor at Ljubljana University, Slovenia.He has been an invited lecturer at numerous international conferences, and is a co-author of more than 450 scientific articles and 20 approved or pending patents. His main interest lies in neurochemistry, where his research is aimed at studying peptides, particularly neuropeptide receptors, and drug delivery via cell-penetrating peptides.

Format
  • Hardback
License and Copyright
© 2024 by the authors; CC BY-NC-ND license
Keywords
transportan; cell-penetrating peptides; transfection; PepFect; NickFect; blood–brain barrier; penetrating peptides; machine learning techniques; drug delivery; prediction server; hepatocellular carcinoma; tumor-penetrating peptides; interfering peptides; alpha-helix stabilization; secondary structure; cell-penetrating peptides; lipid–peptide interaction; peptide engineering; cell delivery; glycan recognition; alpha-beta peptide; endocytosis; immunoglobulin; cell-penetrating peptides; mitochondrial gene therapy; mitochondrial DNA diseases; mitochondria targeting; nanodelivery systems; PEI-based complexes; CFTR-CAL interaction; CFTR stabilizer; cell-penetrating peptide; p.Phe508del mutant; internalization mechanism; cystic fibrosis; protein aggregation; secretion signal peptide; peptide engineering; drug design; lactoferrin; endocytosis; intracellular trafficking; lysosomal degradation; cell-penetrating peptides; solvent; nanoparticle formation; nucleic acid delivery; antimicrobial peptide; antiviral peptide; cell-penetrating peptide; hepatitis B virus Tachyplesin (Tpl); virion secretion; cell-penetrating peptide; oligoarginines; aromatic modification; cell-penetrating peptide; stereoisomers; intracellular uptake; membrane binding; transepithelial permeation; peptide delivery; cell penetrating peptide; bioportide; eyes absent protein; neoblast; planarian; confocal microscopy; stem cell