Reprint

The Molecular and Cellular Basis of Retinal Diseases

Edited by
August 2020
335 pages
  • ISBN978-3-03936-654-5 (Hardback)
  • ISBN978-3-03936-655-2 (PDF)

This is a Reprint of the Special Issue The Molecular and Cellular Basis of Retinal Diseases that was published in

Biology & Life Sciences
Medicine & Pharmacology
Summary

There are more than 300 genes that have been identified which carry mutations that cause various forms of retinal dysfunction and degeneration, making the study of retinal diseases a subject of high relevance. In this compendium of original and review articles, many of the diseases and pathways associated with disorders of the retina are examined using animal models, to provide the reader with a good overview of current retinal research. Within this volume, you will find research reports on many of the most prominent retinal disorders, such as diabetic retinopathy (DR), age-related macular degeneration (AMD), choroidal neovascularization (CNV), and retinitis pigmentosa (RP). We hope that the work presented here will stimulate new ideas and lead to effective treatments for retinal diseases.

Format
  • Hardback
License and Copyright
© 2020 by the authors; CC BY-NC-ND license
Keywords
autoimmune retinopathy; retinal degeneration; Müller cell; single-cell; retinal phenotype; neural infarcts; vascular leakage; sorsby’s fundus dystrophy; hyaluronan; neovascularization; retina; retinal degeneration; immunity; autoimmunity; rhodopsin; citrullination; retinitis pigmentosa; serine; retinal degeneration; diabetic retinopathy; macular degeneration; macular telangiectasia; oxidative stress; sphingolipids; retina; RPE; Müller cells; retinal diseases; noble metals NPs; bio-inspired NPs; drug delivery; iron; retina; transferrin; retinal degeneration; retinitis pigmentosa; retinal pigment epithelium dystrophy; RPE transmigration; Cre-Lox technology; mouse models; peripherin 2; retinal degeneration; retina; tetraspanin; photoreceptor; phosphoinositides; retinal lipids; membrane trafficking; large animal model; inherited retinal disease; progressive retinal atrophy; retinitis pigmentosa; Leber congenital amaurosis; achromatopsia; congenital stationary night blindness; retinitis pigmentosa; knock-in mouse model; congenital disorder of glycosylation; retina; diurnal rhythm; autophagy; retina; diabetes; diabetic retinopathy; visual photoreceptor cell loss; mouse genetic models; retinitis pigmentosa; Leber congenital amaurosis; ciliopathies; MDPs; mitochondrial-derived peptides; Humanin; HNG; SHLPs; MOTS-c; Age-related Macular Degeneration (AMD); neuroprotection; RPE; mitochondria; n/a

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