Reprint
Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides
Edited by
October 2019
212 pages
- ISBN978-3-03921-582-9 (Paperback)
- ISBN978-3-03921-583-6 (PDF)
This book is a reprint of the Special Issue Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides that was published in
Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and kidney functions. NPs have also been implicated in the pathogenesis of several cardiovascular diseases (CVDs), including hypertension, atherosclerosis, heart failure, and stroke. A fine comprehension of the molecular mechanisms dependent from NPs and underlying the promotion of cardiovascular damage has contributed to improve our understanding of the molecular basis of all major CVDs. Finally, the opportunity to target NPs in order to develop new therapeutic tools for a better treatment of CVDs has been developed over the years. The current Special Issue of the Journal covers all major aspects of the molecular implications of NPs in physiology and pathology of the cardiovascular system, including NP-based therapeutic approaches.
Format
- Paperback
License
© 2019 by the authors; CC BY-NC-ND license
Keywords
PCSK9; natriuretic peptides; adipose tissue; lipid metabolism; LDL receptor; insulin; natriuretic peptides; hypertension; stroke; cardiac hypertrophy; linkage analysis; genetic variants; animal models; BNP; NT-proBNP; heart failure; cardiac dysfunction; forensic medicine; postmortem biochemistry; angiotensin receptor–neprilysin inhibitor; natriuretic peptides; renin–angiotensin system; heart failure; arterial hypertension; natriuretic peptide; vascular; endothelial cell; cardiomyocyte; fibroblast; inflammation; heart failure; hypertension; angiogenesis; heart failure; natriuretic peptides; preserved ejection fraction; natriuretic peptides; heart failure; atrial fibrillation; remodeling; Idiopathic Pulmonary Arterial Hypertension (IPAH); Natriuretic Peptide Clearance Receptor (NPR-C) signaling; atrial natriuretic peptide; hypertension; heart failure; cardiometabolic disease; obesity; metabolic syndrome; cGMP; guanylyl cyclase receptor A; natriuretic peptides; natriuretic peptide; cardiorenal syndrome; vasopressor; vasodilator; kidney; medulla; renin-angiotensin-aldosterone system; Atrial Natriuretic peptide; natriuretic peptides; cardiac remodelling; cardiac hypertrophy; vascular homeostasis; atrial natriuretic peptide; guanylyl cyclase/natriuretic peptide receptor-A; gene-knockout; gene-duplication; hypertension; congestive heart failure; natriuretic peptides; arterial hypertension; pulmonary arterial hypertension; heart failure; stroke; atrial fibrillation; ARNi; MANP