Reprint
Molecular Mechanism of Alzheimer's Disease
Edited by
October 2019
228 pages
- ISBN978-3-03921-407-5 (Paperback)
- ISBN978-3-03921-408-2 (PDF)
This book is a reprint of the Special Issue Molecular Mechanism of Alzheimer's Disease that was published in
Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue.
Format
- Paperback
License
© 2019 by the authors; CC BY-NC-ND license
Keywords
γ-secretase; amyloid beta; calcium signaling; drug target discovery; endoplasmic reticulum; inositol 1,4,5-trisphosphate receptor; ion channel; oxidative stress; ryanodine receptor; therapy; amyloid-β oligomer; protein aggregation; AβO receptors; Alzheimer’s disease; neurodegeneration; amyloid β; Alzheimer’s disease; cognitive function; dairy products; dementia; inflammation; microglia; Alzheimer’s disease; yeast; Tau; amyloid β; ubiquitin; aggregation; oligomerization; prion; CDK5R1; lncRNAs; Alzheimer’s disease; miR-15/107; NEAT1; HOTAIR; MALAT1; heat shock response; heat shock protein; Alzheimer’s disease; beta amyloid; yeast; Alzheimer’s disease; complement receptor 1; CR1 length polymorphism; CR1 density; complement C3b/C4b receptor; complement; dementia; molecular biology; neurosciences; genetic risk; Alzheimer’s disease; brain glucose metabolism; neuronal differentiation; neuronal degeneration; Prolyl isomerases; Pin1; type 2 diabetes; type 3 diabetes; miR-34c; dendritic spine; Alzheimer’s disease; Alzheimer’s disease; positron emission tomography (PET); magnetic resonance imaging (MRI); Alzheimer’s disease; cystathionine-γ-lyase CTH gene; DNA methylation; epigenetics; epigenome-wide association study; methylome; methylenetetrahydrofolate reductase MTHFR gene; nutrition; S-adenosylmethionine; vitamin B complex; Alzheimer’s disease; sleep disturbance; sleep fragmentation; slow-wave sleep; amyloid beta; tau; proteostasis; default-mode network; cognitive behavioral therapy for insomnia; APOE gene; apolipoprotein E; DNA methylation; mild cognitive impairment; Hispanics