*4.6. Ocular*

Generally, various drops or ointments are used for ocular infection or inflammation. In these cases, those drugs are easily excreted from the eye very quickly. Therefore, to improve therapeutic efficacy and overcome the repetitive administration of an established ocular dosage, nanofiber-based ocular inserts have been considered and compared with eye drops or similar methods of dosage. Drug-loaded nanofiber scaffolds that allow the controlled release of incorporated drugs can be placed into the ocular mucosa. For example, the use of brimonidine tartrate (BT)-loaded electrospun nanofibers as ocular inserts were used to treat ocular infection and inflammation, which is described in detail in Section 5.1.9 [58].
