*2.1. Materials*

Polycaprolactone (PCL; Mn = 70,000–90,000 determined by Gas Permeation Chromatography), chloroform, *N*,*N*-dimethylformamide (DMF), 1,6-hexamethylenediamine (HMD), Ellmans reagent (DTNB), 2-iminiothiolane (2IT), 2-(*N*-morpholino)-ethanesulfonic acid (MES hydrate), phosphate buffered saline (PBS), *N*-hydroxysuccinimide (NHS), and 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride (EDC) were purchased from Sigma-Aldrich (Saint Louis, MO, USA) and kept at room temperature (RT), with the exception of 2IT which was kept at 4 ◦C and EDC which was kept at −20 ◦C. 4-(dimethylamino) pyridine (DMAP) was purchased from Millipore (Darmstadt, Germany) and kept at RT. Anti-TNF-α antibody [B-C7] was purchased from Abcam (Cambridge, UK) and kept at 4 ◦C until further use. Alexa Fluor® 488 goat anti-mouse rabbit IgG (H + L) and TNF-α human ELISA kit were purchased from Life Technologies (Carlsbad, CA, USA) and kept at 4 ◦C until further use.
