*2.5. Statistical Analysis*

Univariate and multivariate Cox proportional models and the Kaplan–Meier method were used for statistical analyses. Factors with *p* < 0.05 in univariate analysis were included in multivariate analysis when assessing Cox proportional models. Welch's *t*-test, Fisher test, and Wilcoxon's signed rank test were used to assess the associations of TST and other clinical variables. Statistical computations were carried out using the JMP 13.0.0 software program (SAS Institute, Cary, NC, USA). Significance was set at *p* < 0.05.
