*2.12. Statistical Analysis*

If not otherwise indicated, data were obtained from 3 independent experiments with at least 2–3 mice each. Total mice numbers were stated in the figure legends. Statistical significance was evaluated by 1- or 2-way ANOVA followed by Tukey's or Bonferroni multiple comparisons post-hoc test and set at the level of *p* ≤ 0.05. Data analysis was performed with Prism 5.0 software (GraphPad, La Jolla, CA, USA).
