*2.10. Human Tumour Tissue*

Tissues from human prostate carcinomas were obtained during surgery according to local ethical and biohazard regulations. All experiments were performed in strict accordance with local guidelines and regulations. Resected tissue specimens were processed for pathological diagnostic routine in agreemen<sup>t</sup> with institutional standards and diagnoses were made based on current WHO and updated ISUP criteria [11,21]. All studies including human tissue samples were approved by the local ethics committee (Ethik-Kommission) of the University Hospital Essen (Nr. 10-4363 and 10-4051). Human tissue samples were analysed anonymously.
