*2.3. EDI Levels of Sulfonamide Residues Through Fish in Taiwanese Adults*

Average EDI levels extrapolated from average sulfamethazine levels in Taiwanese women and men were 0.001 and 0.002 μg/kg body weight/day, respectively (Table 3). The acceptable daily intake (ADI) level of sulfamethazine residues through food is 0.05 mg/kg, as stipulated by the Joint Food and Agriculture Organization of the United Nations/World Health Organization Expert Committee on Food Additives (JECFA) [1,14]. The obtained EDI levels were determined to be substantially lower than the JECFA-recommended ADI levels of sulfamethazine (Table 3). Moreover, the EDI levels expressed as the percentages of the ADIs were 0.004% and 0.002% in men and women respectively. Taken together, fish consumption led to a low risk assessment for sulfamethazine, with EDIs that are <0.1% of the ADIs in both men as well as women.

**Table 3.** Estimated daily intake (EDI) levels of sulfonamide residues in Taiwanese adults.

