**5. Conclusions**

In summary, we concluded that both short-term and long-term 100 Hz EA stimulation provided significant pain relief for chronic inflammatory pain, and this analgesic effect was related to the suppression of P2X3 in the DRG and SCDH.

**Author Contributions:** Methodology, S.W. and Y.X.; Software, X.L.; Formal Analysis, F.S.; Investigation, J.F.; Data Curation, W.W.; Writing—Original Draft Preparation, X.X.; Writing—Review & Editing, H.S.; Supervision, J.D.; Funding Acquisition, J.F.

**Acknowledgments:** This work was supported by the National Natural Science Foundation of China (8147377, 81603690, 81603692), the Major Scientific and Technological Project of Zhejiang Province (WKJ-ZJ-1419), the Zhejiang First-class Discipline (Chinese Medicine) Funding (Zhejiang Administration Letter (2016) No.6.), and the Talent Project of Zhejiang Association for Science and Technology (2017YCGC004).

**Conflicts of Interest:** The authors declare no conflict of interest.
