*Review* **The Role of Immune Cells and Cytokines in Intestinal Wound Healing**

#### **Xiang Xue \* and Daniel M. Falcon**

Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA; DmFalcon@salud.unm.edu

**\*** Correspondence: xxue@salud.unm.edu

Received: 8 October 2019; Accepted: 29 November 2019; Published: 3 December 2019

**Abstract:** Intestinal wound healing is a complicated process that not only involves epithelial cells but also immune cells. In this brief review, we will focus on discussing the contribution and regulation of four major immune cell types (neutrophils, macrophages, regulatory T cells, and innate lymphoid cells) and four cytokines (interleukin-10, tumor necrosis factor alpha, interleukin-6, and interleukin-22) to the wound repair process in the gut. Better understanding of these immune factors will be important for developing novel targeted therapy.

**Keywords:** immune cells; cytokines; wound healing; intestine; inflammatory bowel disease
