*4.20. Statistical Analysis*

Data are expressed as mean ± standard deviations (SDs), one- or two-way analysis of variance (ANOVA) with Turkey post hoc test was used to analyze the data in multiple groups. The Student's *t*-test was used to evaluate statistically significant differences between the groups. All statistical analyses were performed while using SPSS for Windows, version 18.0 (SPSS Inc., Chicago, IL, USA). A *p* value of less than 0.05 was considered to indicate statistical significance.

## **Supplementary Materials:** Supplementary materials can be found at http://www.mdpi.com/1422-0067/20/20/ 5022/s1.

**Author Contributions:** Methodology, C.-T.S. and W.-F.W.; Project administration, H.-S.L.; Supervision, C.-N.C. and Y.-M.W.; Writing—original draft, C.-H.C. and C.-M.H.; Writing—review & editing, S.-L.L.

**Funding:** This study was supported by the Ministry of Science and Technology, Republic of China. (Grant Nos. MOST 105-2314-B-002-058 -MY2 and MOST 104-2320-B-002-043) and the National Taiwan University Hospital (Grant Nos. NTUH106-S3384 and NTUH105-S2973). The funders had no role in study design, data collection and analysis, decision to publish, or manuscript preparation of the manuscript.

**Conflicts of Interest:** The authors declare no conflict of interest.
