*4.9. Statistical Analysis*

Data was shown as mean ± SD. The data were performed using a student's t-test (for two groups), one-way ANOVA followed by Tukey's test (for more than two groups) and two-way ANOVA followed by multiple comparisons were performed using Graph Pad Prism 5 (San Diego, CA, USA). The *p*-value < 0.05 was considered to be significant, the *p*-value < 0.01 was considered to be extremely significant.

**Author Contributions:** Conceptualization, J.J. and X.Z. (Xiuyue Zhang); software, C.Z. and Y.Z.; formal analysis, J.J. and X.S.; writing—original draft preparation, J.J. and C.Z.; writing—review and editing, X.Z. (Xiaomao Zeng), X.Z. (Xiuyue Zhang) and B.Y.; funding acquisition, Y.S. and X.Z. (Xiuyue Zhang).

**Funding:** The research was funded by the Science and Technology Project of Sichuan Province (2017SZ0019). **Conflicts of Interest:** The authors declare no conflict of interest.
