**2. Immune Cells**

The innate immunity is our first line of nonspecific and rapid defense against pathogens, whereas adaptive immunity confers specific long-lasting memory. Innate immune cells include neutrophils, macrophages, and DCs. The roles of neutrophils and macrophages in wound repair are discussed in detail below. DCs are antigen presenting cells mediating T cell activation and adaptive immunity, thus playing key roles in the crosstalk between innate and adaptive immunity [4].
