*2.1. Tissue Inflammation*

The inflammatory response after tissue damage is an important biological process that is essential for the survival of living organisms [1]. When tissues are damaged by infection, exposure to toxins, or mechanical damage, an inflammatory response is induced by damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PRR) released by dead cells and invading organisms [53]. These molecules provoke a complex inflammatory response characterized by the recruitment, proliferation, and activation of various hematopoietic and non-hematopoietic cells, including neutrophils, macrophages, innate lymphoid cells, natural killer cells, B cells, T cells, fibroblasts, epithelial cells, endothelial cells, and stem cells, which together constitute the cellular response that orchestrates tissue repair [54–56].
