*4.1. Characteristics of Patients*

Lipoaspirates were obtained from three HIV-infected patients who are hemophilic and infected with HIV virus by unheated blood products and were diagnosed as lipodystrophy after HAART [36]. The patient #1 and #3, a 30 years-old man, diagnosed HIV positive when he was 15 years old, and the patient #2, a 46 years-of-old man, was notified HIV-positive when he was at the age of 22 years. The patient #4, a 36 years-old man, diagnosed HIV positive when he was 11 years old. Clinically all patients demonstrated the severe lipoatrophy in the naso-labial, melo-labial, temporal and parotid region of their faces. Patient #1 and #3 were severely lean in their torso, while the patient #2 was moderately built in the torso. The patient #4 was well-built in torso but lean in extremities. The body weights of the HIV-infected patients were 56.9 kg, 59.4 kg, and 70.3 kg, respectively and the body mass indexes (BMI) were 19.92, 21.96, and 21.94, respectively. Lipoaspirates from HIV-infected patients were obtained from abdomen, thighs, back, and shoulders where lipoatrophy was less severe. Lipoaspirates were also obtained from four patients, who are not related to HIV-infection. Their mean weight was 48.6 ± 3.93 kg with BMI 22.91 ± 3.303. The mean age of the HIV-infected patients was 35.5 ± 7.55, while it was 72.0 ± 16.1 in HIV-uninfected patients.
