*3.7. Data Analysis*

At least three individual experiments were conducted for in vitro experiments. Data are presented as mean ± standard error of the mean (SEM). All of the statistical comparisons were performed using one-way ANOVA followed by a Bonferroni post hoc test for multigroup comparisons using GraphPad Prism software (GraphPad Software, San Diego, CA, USA); p-values under 0.05 was considered statistically significant.

**Author Contributions:** Conceptualization; Y.S. and H.-S.K.; Methodology and data analysis, S.-J.O., Y.S., J.-S.A., Y.Y.S. and J.W.Y.; Providing material and supporting experiments, N.P.M., E.A.V., and S.A.F.; Writing-original draft preparation, S.-J.O. and Y.S.; Writing-review and editing, H.K.K., J.H., V.A.S. and H.-S.K.

**Funding:** This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. NRF-2018R1A5A2023879 and NRF-2017R1E1A1A01074316) and partially supported by a clinical research grant from Pusan National University Hospital in 2018.

**Conflicts of Interest:** The authors declare no conflict of interest.
