*3.1. General Procedures*

Optical rotations were measured using a Perkin-Elmer 343 polarimeter. The 1H- and 13C NMR spectra were recorded on an Avance III-700 spectrometer at 700 and 175 MHz, respectively. Chemical shifts were referenced to the corresponding residual solvent signal (δ<sup>H</sup> 3.30/δ<sup>C</sup> 49.60 in CD3OD). The HRESIMS spectra were recorded on a Bruker maXis Impact II mass spectrometer (Bruker, Germany). Low-pressure column liquid chromatography was performed using YMC-GEL ODS-A. HPLC was performed using an Agilent Series 1100 Instrument equipped with a differential refractometer RIDDE14901810 and an YMC-ODS-A (250 × 10 mm) column. Sorbfil Si gel plates (4.5 × 6.0 cm, 5–17 μm, Sorbpolimer, Krasnodar, Russia) were used for thin-layer chromatography. MTT reduction was measured using the F200PRO reader (TECAN, Männedorf, Switzerland).
