*2.3. Western Blotting*

Whole cell protein extraction and western blotting analysis were performed as previously described [29]. Antibodies used are described in Supplementary Materials.

#### *2.4. Aldefluor Assay and Cell Sorting*

Cells with high Aldehyde Dehydrogenase (ALDH) activity was detected and isolated using the AldefluorTM reagent (Stem Cells Technologies, Grenoble, France) as previously described [13].
